Epigenetic regulation by metabolites from the gut microbiome
Issued Date
2022-01-01
Resource Type
ISSN
18762883
eISSN
18762891
Scopus ID
2-s2.0-85143644296
Pubmed ID
36377583
Journal Title
Beneficial Microbes
Volume
13
Issue
6
Start Page
437
End Page
443
Rights Holder(s)
SCOPUS
Bibliographic Citation
Beneficial Microbes Vol.13 No.6 (2022) , 437-443
Suggested Citation
Marín-Tello C. Epigenetic regulation by metabolites from the gut microbiome. Beneficial Microbes Vol.13 No.6 (2022) , 437-443. 443. doi:10.3920/BM2022.0006 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/86244
Title
Epigenetic regulation by metabolites from the gut microbiome
Author(s)
Other Contributor(s)
Abstract
The gut microbiome can metabolise food components, such as dietary fibres and various phytochemicals; and the microbiome can also synthesise some nutrients, for example B vitamins. The metabolites produced by bacteria and other micro-organisms in the colon can have implications for health and disease risk. Some of these metabolites are epigenetically active, and can contribute to changes in the chemical modification and structure of chromatin by affecting the activity and expression of epigenetically-active enzymes, for example histone deacetylases and DNA methyltransferases. The epigenetic activity of such gut microbiome metabolites is reviewed herein.