Effects of Wall Material on Medium-Chain Triglyceride (MCT) Oil Microcapsules Prepared by Spray Drying

dc.contributor.authorSan S.M.
dc.contributor.authorJaturanpinyo M.
dc.contributor.authorLimwikrant W.
dc.contributor.otherMahidol University
dc.date.accessioned2023-06-18T18:13:30Z
dc.date.available2023-06-18T18:13:30Z
dc.date.issued2022-06-01
dc.description.abstractA medium-chain triglyceride (MCT) oil microcapsule was prepared by spray drying. The effects of the wall-material parameters of wall-to-oil ratio (1:1 to 3:1) and type of wall material (gum arabic (GA), whey protein isolate (WPI), and octenyl succinic anhydride (OSA) starch) on the microcapsules were evaluated. The droplet size, size distribution, viscosity, zeta potential, and stability of the emulsions were measured. The spray-dried powder was characterized by its morphology, yield, encapsulation efficiency, and moisture content. The wall material influenced the characteristics of the emulsions and microcapsules. The formulation with a 2:1 wall-to-oil ratio and OSA starch/maltodextrin as the wall material resulted in a small droplet size (0.177 ± 0.002 µm) with high encapsulation efficiency (98.38 ± 0.01%). This formulation had good physical stability over three months under accelerated conditions. Thus, OSA starch/maltodextrin is an appropriate wall material for encapsulating MCT oil.
dc.identifier.citationPharmaceutics Vol.14 No.6 (2022)
dc.identifier.doi10.3390/pharmaceutics14061281
dc.identifier.eissn19994923
dc.identifier.scopus2-s2.0-85132579126
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/86857
dc.rights.holderSCOPUS
dc.subjectPharmacology, Toxicology and Pharmaceutics
dc.titleEffects of Wall Material on Medium-Chain Triglyceride (MCT) Oil Microcapsules Prepared by Spray Drying
dc.typeArticle
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85132579126&origin=inward
oaire.citation.issue6
oaire.citation.titlePharmaceutics
oaire.citation.volume14
oairecerif.author.affiliationMahidol University

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