Risk mapping using serologic surveillance for selected One Health and transboundary diseases in Cambodian goats
Issued Date
2023-04-01
Resource Type
ISSN
19352727
eISSN
19352735
Scopus ID
2-s2.0-85152599630
Pubmed ID
37011099
Journal Title
PLoS Neglected Tropical Diseases
Volume
17
Issue
4
Rights Holder(s)
SCOPUS
Bibliographic Citation
PLoS Neglected Tropical Diseases Vol.17 No.4 (2023)
Suggested Citation
Siengsanan-Lamont J., Kong L., Heng T., Khoeun S., Tum S., Selleck P.W., Gleeson L.J., Blacksell S.D. Risk mapping using serologic surveillance for selected One Health and transboundary diseases in Cambodian goats. PLoS Neglected Tropical Diseases Vol.17 No.4 (2023). doi:10.1371/journal.pntd.0011244 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/82082
Title
Risk mapping using serologic surveillance for selected One Health and transboundary diseases in Cambodian goats
Other Contributor(s)
Abstract
In Cambodia, goat production and meat consumption are customary among Muslim com-munities. Recently, goat meat has gained popularity among Cambodians. Goat farmers use a traditional management system, including grazing, requiring minimal labour. The close proximity between humans and animals could increase the risk of zoonotic disease trans-mission. A serological survey was undertaken to estimate the prevalence of some priority zoonoses and high-impact animal diseases in the Cambodian goat population. A total of 540 samples were collected from goats in six provinces and analysed with commercially available enzyme-linked immunosorbent assays for Brucella species, Q fever (Coxiella bur-netii), Foot and Mouth Disease virus non-structural protein (FMDV NSP) and Peste des Petits Ruminants virus (PPRV). True seroprevalences with a 95% Confidence Interval (CI), taking into account imperfect tests, risk factors and odds ratios (ORs), were calculated to better understand the disease distribution and epidemiology. Independent variables used in statistical modellings included sex, body condition score, age, vaccination history, province and commune, while dependent variables were ELISA test results. The overall true prevalence of antibodies to Brucella spp., C. burnetii, FMDV and PPRV, were 0.1% (95% CI 0.0, 1.0), 7.2% (95% CI 5.3, 9.7), 57.7% (95% CI 53.1, 62.3) and 0.0% (95% CI 0.0, 0.0), respec-tively. There was no identified risk factor for brucellosis and PPR. The two risk factors for C. burnetii seropositivity were sex (p-value = 0.0005) and commune (p-value <0.0001). How-ever, only the OR of C. burnetii seropositive female goat was significant at 9.7 (95% CI 2.7, 35.5) times higher than male. The risk factors of FMD NSP seropositivity were age (p-value = 0.001) and commune (p-value <0.0001). Only the age ’more than two-year-old’ group with a significant OR of 6.2 (95% CI 2.1, 18.4) using the ’up to one-year-old’ group as the refer-ence. In summary, Brucella spp. seroprevalence was low, while no evidence of PPRV antibodies was detected in the goat populations. C. burnetii seroprevalence in female goats was significantly higher than for males, and there were significant differences in C. burnetii seroprevalence between communes. The overall FMDV NSP seroprevalence was high, especially in older animals. Vaccination should be advocated to protect animals from FMDV and improve productivity. As the impacts of these zoonoses on human and animal health were still unknown, further investigation of these zoonotic diseases’ epidemiology is recommended.