Plasmapheresis for Thrombotic Microangiopathy Due to a Post-transplant Lymphoproliferative Disorder
Issued Date
2022-11-01
Resource Type
eISSN
25775820
Scopus ID
2-s2.0-85144101790
Journal Title
OBM Transplantation
Volume
6
Issue
2
Rights Holder(s)
SCOPUS
Bibliographic Citation
OBM Transplantation Vol.6 No.2 (2022)
Suggested Citation
Yu Q., Suknuntha K., Zhong W., Matson D.R., Hess A.S., Rose W.N. Plasmapheresis for Thrombotic Microangiopathy Due to a Post-transplant Lymphoproliferative Disorder. OBM Transplantation Vol.6 No.2 (2022). doi:10.21926/obm.transplant.2202160 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/85383
Title
Plasmapheresis for Thrombotic Microangiopathy Due to a Post-transplant Lymphoproliferative Disorder
Author(s)
Other Contributor(s)
Abstract
We report a case of thrombotic microangiopathy (TMA) diagnosed in the kidney allograft of a 59-year-old woman who had developed plasmacytoma type monomorphic posttransplant lymphoproliferative disorder (PTLD) 30 years after a simultaneous pancreas and kidney transplant. This report demonstrates a rare etiology of TMA in a kidney allograft occurring in association with PTLD-associated monoclonal gammopathy. The main teaching points are: 1) PTLD may be considered in the work-up of a new TMA in the immunosuppressed post-transplant setting, and 2) a paraprotein-associated condition should be considered as clinically relevant coexistent in a patient with TMA because paraproteins are over-represented in patients with otherwise unexplained TMAs.