Contemporary fluid management, humidity, and patent ductus arteriosus management strategy for premature infants among 336 hospitals in Asia
Issued Date
2024-01-01
Resource Type
eISSN
22962360
Scopus ID
2-s2.0-85187909643
Journal Title
Frontiers in Pediatrics
Volume
12
Rights Holder(s)
SCOPUS
Bibliographic Citation
Frontiers in Pediatrics Vol.12 (2024)
Suggested Citation
Hsieh Y.C., Jeng M.J., Lin M.C., Lin Y.J., Rohsiswatmo R., Dewi R., Chee S.C., Neoh S.H., Velasco B.A.E., Imperial M.L.S., Nuntnarumit P., Ngerncham S., Chang Y.S., Kim S.Y., Quek B.H., Amin Z., Kusuda S., Miyake F., Isayama T. Contemporary fluid management, humidity, and patent ductus arteriosus management strategy for premature infants among 336 hospitals in Asia. Frontiers in Pediatrics Vol.12 (2024). doi:10.3389/fped.2024.1336299 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/97736
Title
Contemporary fluid management, humidity, and patent ductus arteriosus management strategy for premature infants among 336 hospitals in Asia
Author's Affiliation
Siriraj Hospital
National Center for Child Health and Development
Taylor's University Malaysia
National Cheng Kung University Hospital
National Yang-Ming University Taiwan
Universitas Indonesia, RSUPN Dr. Cipto Mangunkusumo
National University Hospital
Chung Shan Medical University
Samsung Medical Center, Sungkyunkwan university
Kyorin University
National Chung Hsing University
Faculty of Medicine Ramathibodi Hospital, Mahidol University
KK Women's And Children's Hospital
Providence University Taiwan
Taipei Veterans General Hospital
Veterans General Hospital-Taichung Taiwan
The Catholic University of Korea, College of Medicine
Budhi Mulia Mother and Child Hospital
Philippine Children’s Medical Center
Neonatal Research Network of Japan
Dr. Jose Fabella Memorial Hospital
National Center for Child Health and Development
Taylor's University Malaysia
National Cheng Kung University Hospital
National Yang-Ming University Taiwan
Universitas Indonesia, RSUPN Dr. Cipto Mangunkusumo
National University Hospital
Chung Shan Medical University
Samsung Medical Center, Sungkyunkwan university
Kyorin University
National Chung Hsing University
Faculty of Medicine Ramathibodi Hospital, Mahidol University
KK Women's And Children's Hospital
Providence University Taiwan
Taipei Veterans General Hospital
Veterans General Hospital-Taichung Taiwan
The Catholic University of Korea, College of Medicine
Budhi Mulia Mother and Child Hospital
Philippine Children’s Medical Center
Neonatal Research Network of Japan
Dr. Jose Fabella Memorial Hospital
Corresponding Author(s)
Other Contributor(s)
Abstract
Objectives: The management of patent ductus arteriosus (PDA) is a critical concern in premature infants, and different hospitals may have varying treatment policies, fluid management strategies, and incubator humidity. The Asian Neonatal Network Collaboration (AsianNeo) collected data on prematurity care details from hospitals across Asian countries. The aim of this study was to provide a survey of the current practices in the management of PDA in premature infants in Asian countries. Methods: AsianNeo performed a cross-sectional international questionnaire survey in 2022 to assess the human and physical resources of hospitals and clinical management of very preterm infants. The survey covered various aspects of hospitals resources and clinical management, and data were collected from 337 hospitals across Asia. The data collected were used to compare hospitals resources and clinical management of preterm infants between areas and economic status. Results: The policy of PDA management for preterm infants varied across Asian countries in AsianNeo. Hospitals in Northeast Asia were more likely to perform PDA ligation (p < 0.001) than hospitals in Southeast Asia. Hospitals in Northeast Asia had stricter fluid restrictions in the first 24 h after birth for infants born at <29 weeks gestation (p < 0.001) and on day 14 after birth for infants born at <29 weeks gestation (p < 0.001) compared to hospitals in Southeast Asia. Hospitals in Northeast Asia also had a more humidified environment for infants born between 24 weeks gestation and 25 weeks gestation in the first 72 h after birth (p < 0.001). A logistic regression model predicted that hospitals were more likely to perform PDA ligation for PDA when the hospitals had a stricter fluid planning on day 14 after birth [Odds ratio (OR) of 1.70, p = 0.048], more incubator humidity settings (<80% vs. 80%–89%, OR of 3.35, p = 0.012 and <80% vs. 90%–100%, OR of 5.31, p < 0.001). Conclusions: In advanced economies and Northeast Asia, neonatologists tend to adopt a more conservative approach towards fluid management, maintain higher incubator humidity settings and inclined to perform surgical ligation for PDA.