Leaflet Modification Technique With UNICORN in Failed Aortic Bioprosthesis

dc.contributor.authorChan K.Y.E.
dc.contributor.authorUn K.C.
dc.contributor.authorChiu H.O.A.C.
dc.contributor.authorTai-Leung Chan D.
dc.contributor.authorSze S.Y.
dc.contributor.authorYin W.H.
dc.contributor.authorLee Y.T.
dc.contributor.authorLee Y.T.
dc.contributor.authorLin P.
dc.contributor.authorAbdel-Wahab M.
dc.contributor.authorPop A.M.
dc.contributor.authorTchetche D.
dc.contributor.authorFreeman P.
dc.contributor.authorDe Backer O.
dc.contributor.authorPoon K.
dc.contributor.authorChandavimol M.
dc.contributor.authorTang G.H.L.
dc.contributor.authorWong C.K.
dc.contributor.authorLam S.C.C.
dc.contributor.correspondenceChan K.Y.E.
dc.contributor.otherMahidol University
dc.date.accessioned2026-06-20T18:28:37Z
dc.date.available2026-06-20T18:28:37Z
dc.date.issued2026-06-22
dc.description.abstractThe UNICORN (undermining iatrogenic coronary obstruction with radiofrequency needle) technique was developed in 2022 to reduce the risk for coronary obstruction during valve-in-valve transcatheter aortic valve replacement. The procedure involves traversing the target leaflet with an electrified wire, followed by serial dilation with coronary and peripheral balloons. A balloon-expandable valve is then delivered into the de novo fenestration for intraleaflet deployment. As the balloon-expandable valve expands, the target leaflet is opened and displaced away from the at-risk coronary ostium, resulting in a minimal neoskirt on the target side. Since its introduction, the technique has been adopted at numerous centers worldwide, with various modifications and adaptations. In this paper, a step-by-step description of the UNICORN procedure is provided, and troubleshooting strategies for potential challenges are discussed.
dc.identifier.citationJacc Cardiovascular Interventions Vol.19 No.12 (2026) , 1565-1578
dc.identifier.doi10.1016/j.jcin.2026.04.031
dc.identifier.eissn18767605
dc.identifier.issn19368798
dc.identifier.scopus2-s2.0-105041625957
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/123456789/117435
dc.rights.holderSCOPUS
dc.subjectMedicine
dc.titleLeaflet Modification Technique With UNICORN in Failed Aortic Bioprosthesis
dc.typeReview
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=105041625957&origin=inward
oaire.citation.endPage1578
oaire.citation.issue12
oaire.citation.startPage1565
oaire.citation.titleJacc Cardiovascular Interventions
oaire.citation.volume19
oairecerif.author.affiliationThe University of Queensland
oairecerif.author.affiliationKarolinska Universitetssjukhuset
oairecerif.author.affiliationRigshospitalet
oairecerif.author.affiliationNational Yang-Ming University Taiwan
oairecerif.author.affiliationChina Medical University
oairecerif.author.affiliationQueen Mary Hospital Hong Kong
oairecerif.author.affiliationThe University of Hong Kong Li Ka Shing Faculty of Medicine
oairecerif.author.affiliationRamathibodi Hospital
oairecerif.author.affiliationHerzzentrum Leipzig
oairecerif.author.affiliationThe Prince Charles Hospital
oairecerif.author.affiliationSinai Health System
oairecerif.author.affiliationCheng Hsin General Hospital
oairecerif.author.affiliationClinique Pasteur
oairecerif.author.affiliationGrantham Hospital Hong Kong
oairecerif.author.affiliationAlexian Brothers Medical Center

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