In general, an ideal experimental disease model could represent the true
pathophysiological processes in humans, and should be reproducible, reliable, cost effective
and easy to handle. Concerning liver diseases, the multicellular nature is an essential factor for
developing a model for studying liver diseases such as fibrosis and cancer. Although various in
vitro models have been proposed and currently applied for the liver researches, they are unable
to completely preserve cell-cell interactions of the intact liver. Precision-cut liver slices is an
ex vivo model applicable for studying multicellular diseases with a variety of
physiological/pathophysiological processes and may become a powerful tool for the liver
researches.
Description
The 1st Pharmaceutical Sciences Asia Conference 2019 Theme : Pharmaceutical Sciences toward Health Innovation in the Disruptive Era. Bangkok Midtown Hotel, Thailand. August 22, 2019, page 18-19
