The Benefits of Anthocyanins against Obesity-Induced Inflammation
Issued Date
2022-06-01
Resource Type
eISSN
2218273X
Scopus ID
2-s2.0-85132178793
Pubmed ID
35740977
Journal Title
Biomolecules
Volume
12
Issue
6
Rights Holder(s)
SCOPUS
Bibliographic Citation
Biomolecules Vol.12 No.6 (2022)
Suggested Citation
Ngamsamer C., Sirivarasai J., Sutjarit N. The Benefits of Anthocyanins against Obesity-Induced Inflammation. Biomolecules Vol.12 No.6 (2022). doi:10.3390/biom12060852 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/83715
Title
The Benefits of Anthocyanins against Obesity-Induced Inflammation
Author(s)
Author's Affiliation
Other Contributor(s)
Abstract
Obesity has become a serious public health epidemic because of its associations with chronic conditions such as type 2 diabetes mellitus, hypertension, cardiovascular disease, and cancer. Obesity triggers inflammation marked by the secretion of low-grade inflammatory cytokines including interleukin-6, C-reactive protein, and tumor necrosis factor-α, leading to a condition known as “meta-inflammation”. Currently, there is great interest in studying the treatment of obesity with food-derived bioactive compounds, which have low toxicity and no severe adverse events compared with pharmacotherapeutic agents. Here, we reviewed the beneficial effects of the bioactive compounds known as anthocyanins on obesity-induced inflammation. Foods rich in anthocyanins include tart cherries, red raspberries, black soybeans, blueberries, sweet cherries, strawberries and Queen Garnet plums. These anthocyanin-rich foods have been evaluated in cell culture, animal, and clinical studies, and found to be beneficial for health, reportedly reducing inflammatory markers. One factor in the development of obesity-related inflammation may be dysbiosis of the gut microbiome. Therefore, we focused this review on the in vitro and in vivo effects of anthocyanins on inflammation and the gut microbiota in obesity.