Aortic Root Dilatation Measured by Cardiac Magnetic Resonance in Patients with Repaired Tetralogy of Fallot
Issued Date
2023-06-25
Resource Type
eISSN
15226662
DOI
Scopus ID
2-s2.0-85164028854
Pubmed ID
37401428
Journal Title
The heart surgery forum
Volume
26
Issue
3
Start Page
E277
End Page
E283
Rights Holder(s)
SCOPUS
Bibliographic Citation
The heart surgery forum Vol.26 No.3 (2023) , E277-E283
Suggested Citation
Chungsomprasong P., Kraikriangsri C., Vijarnsorn C., Chanthong P., Durongpisitkul K., Pacharapakornpong T., Kanjanauthai S., Nakyen S., Soongswang J. Aortic Root Dilatation Measured by Cardiac Magnetic Resonance in Patients with Repaired Tetralogy of Fallot. The heart surgery forum Vol.26 No.3 (2023) , E277-E283. E283. doi:10.1532/hsf.5547 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/87906
Title
Aortic Root Dilatation Measured by Cardiac Magnetic Resonance in Patients with Repaired Tetralogy of Fallot
Author's Affiliation
Other Contributor(s)
Abstract
BACKGROUND: Aortic root dilatation (AoD) frequently occurs following repaired tetralogy of Fallot (rTOF). The objective of this study was to assess aortic dimensions, investigate the prevalence of AoD, and identify predictors of AoD in rTOF patients. METHODS: A cross-sectional retrospective study was conducted in repaired TOF patients from 2009 to 2020. Aortic root diameters were measured by cardiac magnetic resonance (CMR). Severe AoD of the aortic sinus (AoS) was defined as a Z-score (z) of >4, reflecting a mean percentile ≥99.99%. RESULTS: Two hundred forty-eight patients, with a median age of 28.2 years (10.2-65.3 years), were included in the study. The median age at the time of repair was 6.6 years (0.8-40.5 years) and the median interval between the repair and CMR study was 18.9 years (2.0-54.8 years). The prevalence of severe AoD was found to be 35.2% when defined by an AoS z greater than 4 and 27.6% when defined by a AoS diameter ≥40 mm, respectively. A total of 101 patients (40.7%) had aortic regurgitation (AR), with 7 patients (2.8%) having moderate AR. Multivariate analysis revealed that severe AoD was only associated with the left ventricular end diastolic volume index (LVEDVi) and a longer duration after repair. The age at the time of repair for TOF was found not to be correlated with the development of AoD. CONCLUSIONS: After repair of TOF, severe AoD was found to be prevalent, but no fatal complications were observed in our study. Mild AR was also commonly observed. Larger LVEDVi and a longer duration after repair were identified as factors associated with the development of severe AoD. Therefore, routine monitoring of AoD is recommended.