Correction to: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (Nature Genetics, (2019), 51, 3, (481-493), 10.1038/s41588-018-0321-7)
Issued Date
2024-01-01
Resource Type
ISSN
10614036
eISSN
15461718
Scopus ID
2-s2.0-85192394658
Pubmed ID
38641645
Journal Title
Nature Genetics
Rights Holder(s)
SCOPUS
Bibliographic Citation
Nature Genetics (2024)
Suggested Citation
Shrine N., Guyatt A.L., Erzurumluoglu A.M., Jackson V.E., Hobbs B.D., Melbourne C.A., Batini C., Fawcett K.A., Song K., Sakornsakolpat P., Li X., Boxall R., Reeve N.F., Obeidat M., Zhao J.H., Wielscher M., Weiss S., Kentistou K.A., Cook J.P., Sun B.B., Zhou J., Hui J., Karrasch S., Imboden M., Harris S.E., Marten J., Enroth S., Kerr S.M., Surakka I., Vitart V., Lehtimäki T., Allen R.J., Bakke P.S., Beaty T.H., Bleecker E.R., Bossé Y., Brandsma C.A., Chen Z., Crapo J.D., Danesh J., DeMeo D.L., Dudbridge F., Ewert R., Gieger C., Gulsvik A., Hansell A.L., Hao K., Hoffman J.D., Hokanson J.E., Homuth G., Joshi P.K., Joubert P., Langenberg C., Li X., Li L., Lin K., Lind L., Locantore N., Luan J., Mahajan A., Maranville J.C., Murray A., Nickle D.C., Packer R., Parker M.M., Paynton M.L., Porteous D.J., Prokopenko D., Qiao D., Rawal R., Runz H., Sayers I., Sin D.D., Smith B.H., Artigas M.S., Sparrow D., Tal-Singer R., Timmers P.R.H.J., Van den Berge M., Whittaker J.C., Woodruff P.G., Yerges-Armstrong L.M., Troyanskaya O.G., Raitakari O.T., Kähönen M., Polašek O., Gyllensten U., Rudan I., Deary I.J., Probst-Hensch N.M., Schulz H., James A.L., Wilson J.F., Stubbe B., Zeggini E., Jarvelin M.R., Wareham N., Silverman E.K., Hayward C., Morris A.P. Correction to: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (Nature Genetics, (2019), 51, 3, (481-493), 10.1038/s41588-018-0321-7). Nature Genetics (2024). doi:10.1038/s41588-024-01752-4 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/98339
Title
Correction to: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (Nature Genetics, (2019), 51, 3, (481-493), 10.1038/s41588-018-0321-7)
Author(s)
Shrine N.
Guyatt A.L.
Erzurumluoglu A.M.
Jackson V.E.
Hobbs B.D.
Melbourne C.A.
Batini C.
Fawcett K.A.
Song K.
Sakornsakolpat P.
Li X.
Boxall R.
Reeve N.F.
Obeidat M.
Zhao J.H.
Wielscher M.
Weiss S.
Kentistou K.A.
Cook J.P.
Sun B.B.
Zhou J.
Hui J.
Karrasch S.
Imboden M.
Harris S.E.
Marten J.
Enroth S.
Kerr S.M.
Surakka I.
Vitart V.
Lehtimäki T.
Allen R.J.
Bakke P.S.
Beaty T.H.
Bleecker E.R.
Bossé Y.
Brandsma C.A.
Chen Z.
Crapo J.D.
Danesh J.
DeMeo D.L.
Dudbridge F.
Ewert R.
Gieger C.
Gulsvik A.
Hansell A.L.
Hao K.
Hoffman J.D.
Hokanson J.E.
Homuth G.
Joshi P.K.
Joubert P.
Langenberg C.
Li X.
Li L.
Lin K.
Lind L.
Locantore N.
Luan J.
Mahajan A.
Maranville J.C.
Murray A.
Nickle D.C.
Packer R.
Parker M.M.
Paynton M.L.
Porteous D.J.
Prokopenko D.
Qiao D.
Rawal R.
Runz H.
Sayers I.
Sin D.D.
Smith B.H.
Artigas M.S.
Sparrow D.
Tal-Singer R.
Timmers P.R.H.J.
Van den Berge M.
Whittaker J.C.
Woodruff P.G.
Yerges-Armstrong L.M.
Troyanskaya O.G.
Raitakari O.T.
Kähönen M.
Polašek O.
Gyllensten U.
Rudan I.
Deary I.J.
Probst-Hensch N.M.
Schulz H.
James A.L.
Wilson J.F.
Stubbe B.
Zeggini E.
Jarvelin M.R.
Wareham N.
Silverman E.K.
Hayward C.
Morris A.P.
Guyatt A.L.
Erzurumluoglu A.M.
Jackson V.E.
Hobbs B.D.
Melbourne C.A.
Batini C.
Fawcett K.A.
Song K.
Sakornsakolpat P.
Li X.
Boxall R.
Reeve N.F.
Obeidat M.
Zhao J.H.
Wielscher M.
Weiss S.
Kentistou K.A.
Cook J.P.
Sun B.B.
Zhou J.
Hui J.
Karrasch S.
Imboden M.
Harris S.E.
Marten J.
Enroth S.
Kerr S.M.
Surakka I.
Vitart V.
Lehtimäki T.
Allen R.J.
Bakke P.S.
Beaty T.H.
Bleecker E.R.
Bossé Y.
Brandsma C.A.
Chen Z.
Crapo J.D.
Danesh J.
DeMeo D.L.
Dudbridge F.
Ewert R.
Gieger C.
Gulsvik A.
Hansell A.L.
Hao K.
Hoffman J.D.
Hokanson J.E.
Homuth G.
Joshi P.K.
Joubert P.
Langenberg C.
Li X.
Li L.
Lin K.
Lind L.
Locantore N.
Luan J.
Mahajan A.
Maranville J.C.
Murray A.
Nickle D.C.
Packer R.
Parker M.M.
Paynton M.L.
Porteous D.J.
Prokopenko D.
Qiao D.
Rawal R.
Runz H.
Sayers I.
Sin D.D.
Smith B.H.
Artigas M.S.
Sparrow D.
Tal-Singer R.
Timmers P.R.H.J.
Van den Berge M.
Whittaker J.C.
Woodruff P.G.
Yerges-Armstrong L.M.
Troyanskaya O.G.
Raitakari O.T.
Kähönen M.
Polašek O.
Gyllensten U.
Rudan I.
Deary I.J.
Probst-Hensch N.M.
Schulz H.
James A.L.
Wilson J.F.
Stubbe B.
Zeggini E.
Jarvelin M.R.
Wareham N.
Silverman E.K.
Hayward C.
Morris A.P.
Author's Affiliation
Siriraj Hospital
Gossamer Bio
MRC Centre for Environment and Health
University of Dundee School of Medicine
College of Health and Life Sciences
School of Engineering and Applied Science
Department of Public Health and Primary Care
Fimlab Laboratoriot Oy
Edinburgh Medical School
VA Boston Healthcare System
Simons Foundation
Centro de Investigación Biomédica En Red de Salud Mental
Terveyden ja Hyvinvoinnin Laitos
National Jewish Health
The Wellcome Centre for Human Genetics
GlaxoSmithKline, USA
University of Western Australia, School of Medicine and Pharmacology
School of Medicine, University of Split
Centre for Heart Lung Innovation
Institut Universitaire de Cardiologie et de pneumologie de Québec - Université Laval
University of Leicester
Université Laval
The University of Western Australia
Universitetet i Bergen
University of Colorado Anschutz Medical Campus
Walter and Eliza Hall Institute of Medical Research
The University of Edinburgh
University of Melbourne
Sir Charles Gairdner Hospital
Turun Yliopistollinen Keskussairaala
Helmholtz Center Munich German Research Center for Environmental Health
University of California, San Francisco
Universität Basel
Swiss Tropical and Public Health Institute Swiss TPH
Universitat Autònoma de Barcelona
St Mary's Hospital
Universitätsmedizin Greifswald
Clinical Trial Service Unit and Epidemiological Studies Unit
University of Arizona College of Medicine – Tucson
University of Liverpool
GlaxoSmithKline plc.
Addenbrooke's Hospital
Brigham and Women's Hospital
Oulu University Hospital
University of Nottingham
Faculty of Medicine
Icahn School of Medicine at Mount Sinai
Oulun Yliopisto
MRC Human Genetics Unit
Hospital Universitari Vall d'Hebron
Lääketieteellinen Tiedekunta
University of Aberdeen School of Medicine, Medical Sciences and Nutrition
University of Edinburgh, College of Medicine and Veterinary Medicine
The University of British Columbia
MRC Epidemiology Unit
University Hospital of Tampere
Merck & Co., Inc.
Boston University Chobanian & Avedisian School of Medicine
Johns Hopkins Bloomberg School of Public Health
Universitair Medisch Centrum Groningen
Wellcome Sanger Institute
Peking University Health Science Center
Uppsala Universitet
Princeton University
Helsingin Yliopisto
University of Oxford Medical Sciences Division
University of Münster
Klinikum der Universität München
Member of the German Center for Lung Research (DZL)
Gossamer Bio
MRC Centre for Environment and Health
University of Dundee School of Medicine
College of Health and Life Sciences
School of Engineering and Applied Science
Department of Public Health and Primary Care
Fimlab Laboratoriot Oy
Edinburgh Medical School
VA Boston Healthcare System
Simons Foundation
Centro de Investigación Biomédica En Red de Salud Mental
Terveyden ja Hyvinvoinnin Laitos
National Jewish Health
The Wellcome Centre for Human Genetics
GlaxoSmithKline, USA
University of Western Australia, School of Medicine and Pharmacology
School of Medicine, University of Split
Centre for Heart Lung Innovation
Institut Universitaire de Cardiologie et de pneumologie de Québec - Université Laval
University of Leicester
Université Laval
The University of Western Australia
Universitetet i Bergen
University of Colorado Anschutz Medical Campus
Walter and Eliza Hall Institute of Medical Research
The University of Edinburgh
University of Melbourne
Sir Charles Gairdner Hospital
Turun Yliopistollinen Keskussairaala
Helmholtz Center Munich German Research Center for Environmental Health
University of California, San Francisco
Universität Basel
Swiss Tropical and Public Health Institute Swiss TPH
Universitat Autònoma de Barcelona
St Mary's Hospital
Universitätsmedizin Greifswald
Clinical Trial Service Unit and Epidemiological Studies Unit
University of Arizona College of Medicine – Tucson
University of Liverpool
GlaxoSmithKline plc.
Addenbrooke's Hospital
Brigham and Women's Hospital
Oulu University Hospital
University of Nottingham
Faculty of Medicine
Icahn School of Medicine at Mount Sinai
Oulun Yliopisto
MRC Human Genetics Unit
Hospital Universitari Vall d'Hebron
Lääketieteellinen Tiedekunta
University of Aberdeen School of Medicine, Medical Sciences and Nutrition
University of Edinburgh, College of Medicine and Veterinary Medicine
The University of British Columbia
MRC Epidemiology Unit
University Hospital of Tampere
Merck & Co., Inc.
Boston University Chobanian & Avedisian School of Medicine
Johns Hopkins Bloomberg School of Public Health
Universitair Medisch Centrum Groningen
Wellcome Sanger Institute
Peking University Health Science Center
Uppsala Universitet
Princeton University
Helsingin Yliopisto
University of Oxford Medical Sciences Division
University of Münster
Klinikum der Universität München
Member of the German Center for Lung Research (DZL)
Corresponding Author(s)
Other Contributor(s)
Abstract
Correction to: Nature Geneticshttps://doi.org/10.1038/s41588-018-0321-7, published online 25 February 2019. In the version of the article initially published, unconsented individuals were erroneously included in SPIROMICS consortium results. The analysis has now been repeated with the unconsented individuals removed. The change in the results does not affect the conclusions in the paper. The corrections required to the paper are as follows: In the third paragraph of the “Association with FEV1/FVC and COPD in multiple ancestries” section: “(n = 6,979 cases and 3,915 controls)”, should be “(n = 6,964 cases and 3,904 controls)” and “P = 2.87 × 10–75” should be “P = 2.21 × 10–75”. In the fourth paragraph of the “Association with FEV1/FVC and COPD in multiple ancestries” section: “4.73 (95% CI: [3.79, 5.90]), P = 3.00 × 10−43”, should be “4.71 (95% CI: [3.77, 5.87]), P = 7.24 × 10−43”. In the Fig. 3b table, the SPIROMICS row: “1.54, 1.38, 1.72, 4.47 × 10–14, 988, 537”, should be “1.55, 1.39, 1.74, 6.80 × 10–14, 973, 526”; and the Meta-analysis row: “1.55, 1.48, 1.62, 1.48 × 10–75, 6,979, 3,915”, should be “1.55, 1.48, 1.62, 2.21 × 10–75, 6,964, 3,904”. In the final paragraph of the Discussion: “The 279-variant GRS we constructed was associated with a 4.73-fold increased relative risk…”, should be “The 279-variant GRS we constructed was associated with a 4.71-fold increased relative risk…” In the fifth paragraph of the “Effect of genetic risk score on COPD susceptibility in multiple ancestries” section in the Methods: “SPIROMICS (988 cases, 537 controls)”, should be “SPIROMICS (973 cases, 526 controls)”. In the third paragraph of the “Association with FEV1/FVC and COPD in multiple ancestries” section: “(n = 6,979 cases and 3,915 controls)”, should be “(n = 6,964 cases and 3,904 controls)” and “P = 2.87 × 10–75” should be “P = 2.21 × 10–75”. In the fourth paragraph of the “Association with FEV1/FVC and COPD in multiple ancestries” section: “4.73 (95% CI: [3.79, 5.90]), P = 3.00 × 10−43”, should be “4.71 (95% CI: [3.77, 5.87]), P = 7.24 × 10−43”. In the Fig. 3b table, the SPIROMICS row: “1.54, 1.38, 1.72, 4.47 × 10–14, 988, 537”, should be “1.55, 1.39, 1.74, 6.80 × 10–14, 973, 526”; and the Meta-analysis row: “1.55, 1.48, 1.62, 1.48 × 10–75, 6,979, 3,915”, should be “1.55, 1.48, 1.62, 2.21 × 10–75, 6,964, 3,904”. In the final paragraph of the Discussion: “The 279-variant GRS we constructed was associated with a 4.73-fold increased relative risk…”, should be “The 279-variant GRS we constructed was associated with a 4.71-fold increased relative risk…” In the fifth paragraph of the “Effect of genetic risk score on COPD susceptibility in multiple ancestries” section in the Methods: “SPIROMICS (988 cases, 537 controls)”, should be “SPIROMICS (973 cases, 526 controls)”. The correction is due to 26 unconsented SPIROMICS samples being originally included in the analysis. The analyses that previously included these samples have been rerun with data from these 26 samples removed. Supplementary Information accompanies the online version of this amendment and includes: Updated Supplementary Text and Figures wherein we have changed: On page 23 (description of SPIROMICS cohort) the number of COPD cases has been changed from 988 to 973 and controls from 537 to 526. Supplementary Figure 9 – the forest plots have been updated for the new results for association with 279 variants after reanalysis of SPIROMICS. Supplementary Table 20 – the demographics for SPIROMICS have been updated. Supplementary Table 21 – the results rows for the SPIROMICS and “Meta-analysis of 5 European-ancestry study groups” have been updated. Supplementary Table 22 – The “Meta-analysis of 5 European cohorts” columns have been updated after SPIROMICS reanalysis. Updated Supplementary Tables wherein we have changed: Supplementary Table 29 – columns X–Z (“Meta-analysis of 5 external European-ancestry COPD cohorts (Cases = 6,964; Controls = 3,904)”) after reanalysis of SPIROMICS data. Updated Supplementary Text and Figures wherein we have changed: On page 23 (description of SPIROMICS cohort) the number of COPD cases has been changed from 988 to 973 and controls from 537 to 526. Supplementary Figure 9 – the forest plots have been updated for the new results for association with 279 variants after reanalysis of SPIROMICS. Supplementary Table 20 – the demographics for SPIROMICS have been updated. Supplementary Table 21 – the results rows for the SPIROMICS and “Meta-analysis of 5 European-ancestry study groups” have been updated. Supplementary Table 22 – The “Meta-analysis of 5 European cohorts” columns have been updated after SPIROMICS reanalysis. Updated Supplementary Tables wherein we have changed: Supplementary Table 29 – columns X–Z (“Meta-analysis of 5 external European-ancestry COPD cohorts (Cases = 6,964; Controls = 3,904)”) after reanalysis of SPIROMICS data.