Global survey of women’s awareness of pregnancy- and postpartum-associated venous thromboembolism (World Thrombosis Day 2025)
1
Issued Date
2026-03-01
Resource Type
eISSN
24750379
Scopus ID
2-s2.0-105036240936
Journal Title
Research and Practice in Thrombosis and Haemostasis
Volume
10
Issue
3
Rights Holder(s)
SCOPUS
Bibliographic Citation
Research and Practice in Thrombosis and Haemostasis Vol.10 No.3 (2026)
Suggested Citation
Di Nisio M., Mahé I., Sadeghipour P., Suviraj J., Rashid A., O’Neill A.M., Hunt B.J., Hadim S., Ghotbizadeh F., Porreca E., Okoye H., Liberati M., Gumulec J., Middeldorp S., Ay C., Hermans C., Monreal M., Casais P., Potere N., Candeloro M., Castellucci L.A., Connors J.M., Wendelboe A.M., Hsu D., Lee L.H., Bang S.M., Morishita E., Angchaisuksiri P., Duerschmied D., Madaro B., Rimann L., Clark C.R., Potter C., De Paula E.V., Barco S. Global survey of women’s awareness of pregnancy- and postpartum-associated venous thromboembolism (World Thrombosis Day 2025). Research and Practice in Thrombosis and Haemostasis Vol.10 No.3 (2026). doi:10.1016/j.rpth.2026.103421 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/116402
Title
Global survey of women’s awareness of pregnancy- and postpartum-associated venous thromboembolism (World Thrombosis Day 2025)
Author(s)
Di Nisio M.
Mahé I.
Sadeghipour P.
Suviraj J.
Rashid A.
O’Neill A.M.
Hunt B.J.
Hadim S.
Ghotbizadeh F.
Porreca E.
Okoye H.
Liberati M.
Gumulec J.
Middeldorp S.
Ay C.
Hermans C.
Monreal M.
Casais P.
Potere N.
Candeloro M.
Castellucci L.A.
Connors J.M.
Wendelboe A.M.
Hsu D.
Lee L.H.
Bang S.M.
Morishita E.
Angchaisuksiri P.
Duerschmied D.
Madaro B.
Rimann L.
Clark C.R.
Potter C.
De Paula E.V.
Barco S.
Mahé I.
Sadeghipour P.
Suviraj J.
Rashid A.
O’Neill A.M.
Hunt B.J.
Hadim S.
Ghotbizadeh F.
Porreca E.
Okoye H.
Liberati M.
Gumulec J.
Middeldorp S.
Ay C.
Hermans C.
Monreal M.
Casais P.
Potere N.
Candeloro M.
Castellucci L.A.
Connors J.M.
Wendelboe A.M.
Hsu D.
Lee L.H.
Bang S.M.
Morishita E.
Angchaisuksiri P.
Duerschmied D.
Madaro B.
Rimann L.
Clark C.R.
Potter C.
De Paula E.V.
Barco S.
Author's Affiliation
Brigham and Women's Hospital
Universität Zürich
Universidade Estadual de Campinas
Universidad de Buenos Aires
Medizinische Universität Wien
Radboud University Medical Center
UniversitatsSpital Zurich
University of G. d'Annunzio Chieti and Pescara
Universitätsmedizin Mainz
Guy's and St Thomas' NHS Foundation Trust
University of Nigeria
Seoul National University Bundang Hospital
Cliniques Universitaires Saint-Luc
Duke-NUS Medical School
Singapore General Hospital
Universitätsklinikum Mannheim
Ostravská Univerzita v Ostrave
Ramathibodi Hospital
Universidad Católica de Murcia
Kanazawa University Graduate School of Medical Sciences
Imam Khomeini Hospital
L’École de médecine
Hopital Louis-Mourier
Sir Ganga Ram Hospital
Shaheed Rajaie Cardiovascular Medical and Research Center
University Hospital in Ostrava
Kanazawa University Hospital
Fay W. Boozman College of Public Health
King's Mill Hospital
Università degli Studi dell'Insubria Varese, Facoltà di Medicina e Chirurgia
International Society on Thrombosis and Haemostasis
Thrombosis Ireland
Liverpool Hospital
Universität Zürich
Universidade Estadual de Campinas
Universidad de Buenos Aires
Medizinische Universität Wien
Radboud University Medical Center
UniversitatsSpital Zurich
University of G. d'Annunzio Chieti and Pescara
Universitätsmedizin Mainz
Guy's and St Thomas' NHS Foundation Trust
University of Nigeria
Seoul National University Bundang Hospital
Cliniques Universitaires Saint-Luc
Duke-NUS Medical School
Singapore General Hospital
Universitätsklinikum Mannheim
Ostravská Univerzita v Ostrave
Ramathibodi Hospital
Universidad Católica de Murcia
Kanazawa University Graduate School of Medical Sciences
Imam Khomeini Hospital
L’École de médecine
Hopital Louis-Mourier
Sir Ganga Ram Hospital
Shaheed Rajaie Cardiovascular Medical and Research Center
University Hospital in Ostrava
Kanazawa University Hospital
Fay W. Boozman College of Public Health
King's Mill Hospital
Università degli Studi dell'Insubria Varese, Facoltà di Medicina e Chirurgia
International Society on Thrombosis and Haemostasis
Thrombosis Ireland
Liverpool Hospital
Corresponding Author(s)
Other Contributor(s)
Abstract
Background: Venous thromboembolism (VTE) is a leading cause of maternal morbidity and mortality, yet women’s awareness during pregnancy and postpartum is not well characterized. Objectives: To assess education and awareness of pregnancy-associated VTE across countries and healthcare systems, including sources of information, perceived understanding, and experiences with anticoagulation. Methods: We conducted a cross-sectional online survey (15 languages), endorsed by the World Thrombosis Day campaign, of females who were pregnant or ≤12 months postpartum (October 2024 and September 2025). Descriptive analyses and subgroup comparisons were performed. Results: Of 3043 responses, 3025 were analyzed. Overall, 69.8% reported no VTE education during pregnancy or the postpartum period, and 1.1% received education only at diagnosis, resulting in 70.9% with no or delayed VTE education. Upon delivery, comprehension was limited, with 36.2%, 46.8%, and 9.2% of females reporting full, partial, and poor understanding, respectively. Only 10.9% of females received instructions on VTE manifestations; among these, 16.3% were not advised to seek urgent care for suspected VTE events. Knowledge of pulmonary embolism-related signs was particularly poor. Prior VTE was reported in 13.3%, and 21.4% had ever used anticoagulants. Among participants who had discussed thromboprophylaxis and/or received anticoagulants, 32.4% were unaware of bleeding risks. Approximately 20% of those informed reported psychological distress related to VTE information. Education rates differed by age, education level, ethnicity, region, and reproductive factors. Conclusion: VTE education during pregnancy and postpartum is infrequent and unevenly distributed. Enhanced educational interventions embedded within antenatal and postnatal care pathways are urgently needed to improve VTE awareness, symptom recognition, and informed decision-making.