Vulnerable newborn types: analysis of subnational, population-based birth cohorts for 541 285 live births in 23 countries, 2000–2021
Issued Date
2023-01-01
Resource Type
ISSN
14700328
eISSN
14710528
Scopus ID
2-s2.0-85158151659
Journal Title
BJOG: An International Journal of Obstetrics and Gynaecology
Rights Holder(s)
SCOPUS
Bibliographic Citation
BJOG: An International Journal of Obstetrics and Gynaecology (2023)
Suggested Citation
Erchick D.J., Hazel E.A., Katz J., Lee A.C.C., Diaz M., Wu L.S.F., Yoshida S., Bahl R., Grandi C., Labrique A.B., Rashid M., Ahmed S., Roy A.D., Haque R., Shaikh S., Baqui A.H., Saha S.K., Khanam R., Rahman S., Shapiro R., Zash R., Silveira M.F., Buffarini R., Kolsteren P., Lachat C., Huybregts L., Roberfroid D., Zeng L., Zhu Z., He J., Qiu X., Gebreyesus S.H., Tesfamariam K., Bekele D., Chan G., Baye E., Workneh F., Asante K.P., Kaali E.B., Adu-Afarwuah S., Dewey K.G., Gyaase S., Wylie B.J., Kirkwood B.R., Manu A., Thulasiraj R.D., Tielsch J., Chowdhury R., Taneja S., Babu G.R., Shriyan P., Ashorn P., Maleta K., Ashorn U., Mangani C., Acevedo-Gallegos S., Rodriguez-Sibaja M.J., Khatry S.K., LeClerq S.C., Mullany L.C., Jehan F., Ilyas M., Rogerson S.J., Unger H.W., Ghosh R., Musange S., Ramokolo V., Zembe-Mkabile W., Lazzerini M., Rishard M., Wang D., Fawzi W.W., Minja D.T.R., Schmiegelow C., Masanja H., Smith E., Lusingu J.P.A., Msemo O.A., Kabole F.M., Slim S.N., Keentupthai P., Mongkolchati A., Kajubi R., Kakuru A., Waiswa P., Walker D., Hamer D.H., Semrau K.E.A., Chaponda E.B., Chico R.M., Banda B., Musokotwane K., Manasyan A., Pry J.M., Chasekwa B., Humphrey J., Black R.E., Ali H., Christian P., Klemm R.D.W. Vulnerable newborn types: analysis of subnational, population-based birth cohorts for 541 285 live births in 23 countries, 2000–2021. BJOG: An International Journal of Obstetrics and Gynaecology (2023). doi:10.1111/1471-0528.17510 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/82788
Title
Vulnerable newborn types: analysis of subnational, population-based birth cohorts for 541 285 live births in 23 countries, 2000–2021
Author(s)
Erchick D.J.
Hazel E.A.
Katz J.
Lee A.C.C.
Diaz M.
Wu L.S.F.
Yoshida S.
Bahl R.
Grandi C.
Labrique A.B.
Rashid M.
Ahmed S.
Roy A.D.
Haque R.
Shaikh S.
Baqui A.H.
Saha S.K.
Khanam R.
Rahman S.
Shapiro R.
Zash R.
Silveira M.F.
Buffarini R.
Kolsteren P.
Lachat C.
Huybregts L.
Roberfroid D.
Zeng L.
Zhu Z.
He J.
Qiu X.
Gebreyesus S.H.
Tesfamariam K.
Bekele D.
Chan G.
Baye E.
Workneh F.
Asante K.P.
Kaali E.B.
Adu-Afarwuah S.
Dewey K.G.
Gyaase S.
Wylie B.J.
Kirkwood B.R.
Manu A.
Thulasiraj R.D.
Tielsch J.
Chowdhury R.
Taneja S.
Babu G.R.
Shriyan P.
Ashorn P.
Maleta K.
Ashorn U.
Mangani C.
Acevedo-Gallegos S.
Rodriguez-Sibaja M.J.
Khatry S.K.
LeClerq S.C.
Mullany L.C.
Jehan F.
Ilyas M.
Rogerson S.J.
Unger H.W.
Ghosh R.
Musange S.
Ramokolo V.
Zembe-Mkabile W.
Lazzerini M.
Rishard M.
Wang D.
Fawzi W.W.
Minja D.T.R.
Schmiegelow C.
Masanja H.
Smith E.
Lusingu J.P.A.
Msemo O.A.
Kabole F.M.
Slim S.N.
Keentupthai P.
Mongkolchati A.
Kajubi R.
Kakuru A.
Waiswa P.
Walker D.
Hamer D.H.
Semrau K.E.A.
Chaponda E.B.
Chico R.M.
Banda B.
Musokotwane K.
Manasyan A.
Pry J.M.
Chasekwa B.
Humphrey J.
Black R.E.
Ali H.
Christian P.
Klemm R.D.W.
Hazel E.A.
Katz J.
Lee A.C.C.
Diaz M.
Wu L.S.F.
Yoshida S.
Bahl R.
Grandi C.
Labrique A.B.
Rashid M.
Ahmed S.
Roy A.D.
Haque R.
Shaikh S.
Baqui A.H.
Saha S.K.
Khanam R.
Rahman S.
Shapiro R.
Zash R.
Silveira M.F.
Buffarini R.
Kolsteren P.
Lachat C.
Huybregts L.
Roberfroid D.
Zeng L.
Zhu Z.
He J.
Qiu X.
Gebreyesus S.H.
Tesfamariam K.
Bekele D.
Chan G.
Baye E.
Workneh F.
Asante K.P.
Kaali E.B.
Adu-Afarwuah S.
Dewey K.G.
Gyaase S.
Wylie B.J.
Kirkwood B.R.
Manu A.
Thulasiraj R.D.
Tielsch J.
Chowdhury R.
Taneja S.
Babu G.R.
Shriyan P.
Ashorn P.
Maleta K.
Ashorn U.
Mangani C.
Acevedo-Gallegos S.
Rodriguez-Sibaja M.J.
Khatry S.K.
LeClerq S.C.
Mullany L.C.
Jehan F.
Ilyas M.
Rogerson S.J.
Unger H.W.
Ghosh R.
Musange S.
Ramokolo V.
Zembe-Mkabile W.
Lazzerini M.
Rishard M.
Wang D.
Fawzi W.W.
Minja D.T.R.
Schmiegelow C.
Masanja H.
Smith E.
Lusingu J.P.A.
Msemo O.A.
Kabole F.M.
Slim S.N.
Keentupthai P.
Mongkolchati A.
Kajubi R.
Kakuru A.
Waiswa P.
Walker D.
Hamer D.H.
Semrau K.E.A.
Chaponda E.B.
Chico R.M.
Banda B.
Musokotwane K.
Manasyan A.
Pry J.M.
Chasekwa B.
Humphrey J.
Black R.E.
Ali H.
Christian P.
Klemm R.D.W.
Author's Affiliation
Kamuzu University of Health Sciences
St. Paul‘s Hospital Millennium Medical College
Public Health Foundation of India
Addis Continental Institute of Public Health
Ariadne Labs
Infectious Diseases Research Collaboration
The Peter Doherty Institute for Infection and Immunity
Nepal Nutrition Intervention Project-Sarlahi
University of Rwanda
Centre for Infectious Disease Research in Zambia
University of Zambia
Kintampo Health Research Centre
Makerere University School of Public Health
Ministry of Health Zanzibar
Ifakara Health Institute
National Institute for Medical Research Tanga
Addis Ababa University
University of Colombo
Aravind Eye Care System
Society for Applied Studies Kolkata
The Aga Khan University
Instituto Nacional de Perinatologia
Universiteit Gent
University of Namur, Faculty of Medicine
Harvard T.H. Chan School of Public Health
Milken Institute School of Public Health
IRCCS Burlo Garofolo
London School of Hygiene & Tropical Medicine
Ubon Ratchathani University
Beth Israel Deaconess Medical Center
North-West University
School of Basic Medical Sciences
South African Medical Research Council
Columbia University Irving Medical Center
Organisation Mondiale de la Santé
The University of Alabama at Birmingham
Menzies School of Health Research
University of California, San Francisco
Boston University
School of Public Health
George Mason University
University of Ghana
Brigham and Women's Hospital
Universidade Federal de Pelotas
University of California, Davis
Gertrude H. Sergievsky Center
Faculty of Health and Medical Sciences
Guangzhou Medical University
Mahidol University
Karolinska Institutet
University Hospital of Tampere
UNICEF
Johns Hopkins Bloomberg School of Public Health
Uppsala Universitet
Harvard Medical School
University of South Africa
International Food Policy Research Institute
IntraHealth International
JiVitA Maternal and Child Health & Nutrition Research Project
Projahnmo Research Foundation
Zvitambo Institute for Maternal and Child Health Research
Child Health Research Foundation
University Obstetrics Unit
Argentine Society of Medicine
St. Paul‘s Hospital Millennium Medical College
Public Health Foundation of India
Addis Continental Institute of Public Health
Ariadne Labs
Infectious Diseases Research Collaboration
The Peter Doherty Institute for Infection and Immunity
Nepal Nutrition Intervention Project-Sarlahi
University of Rwanda
Centre for Infectious Disease Research in Zambia
University of Zambia
Kintampo Health Research Centre
Makerere University School of Public Health
Ministry of Health Zanzibar
Ifakara Health Institute
National Institute for Medical Research Tanga
Addis Ababa University
University of Colombo
Aravind Eye Care System
Society for Applied Studies Kolkata
The Aga Khan University
Instituto Nacional de Perinatologia
Universiteit Gent
University of Namur, Faculty of Medicine
Harvard T.H. Chan School of Public Health
Milken Institute School of Public Health
IRCCS Burlo Garofolo
London School of Hygiene & Tropical Medicine
Ubon Ratchathani University
Beth Israel Deaconess Medical Center
North-West University
School of Basic Medical Sciences
South African Medical Research Council
Columbia University Irving Medical Center
Organisation Mondiale de la Santé
The University of Alabama at Birmingham
Menzies School of Health Research
University of California, San Francisco
Boston University
School of Public Health
George Mason University
University of Ghana
Brigham and Women's Hospital
Universidade Federal de Pelotas
University of California, Davis
Gertrude H. Sergievsky Center
Faculty of Health and Medical Sciences
Guangzhou Medical University
Mahidol University
Karolinska Institutet
University Hospital of Tampere
UNICEF
Johns Hopkins Bloomberg School of Public Health
Uppsala Universitet
Harvard Medical School
University of South Africa
International Food Policy Research Institute
IntraHealth International
JiVitA Maternal and Child Health & Nutrition Research Project
Projahnmo Research Foundation
Zvitambo Institute for Maternal and Child Health Research
Child Health Research Foundation
University Obstetrics Unit
Argentine Society of Medicine
Other Contributor(s)
Abstract
Objective: To examine prevalence of novel newborn types among 541 285 live births in 23 countries from 2000 to 2021. Design: Descriptive multi-country secondary data analysis. Setting: Subnational, population-based birth cohort studies (n = 45) in 23 low- and middle-income countries (LMICs) spanning 2000–2021. Population: Liveborn infants. Methods: Subnational, population-based studies with high-quality birth outcome data from LMICs were invited to join the Vulnerable Newborn Measurement Collaboration. We defined distinct newborn types using gestational age (preterm [PT], term [T]), birthweight for gestational age using INTERGROWTH-21st standards (small for gestational age [SGA], appropriate for gestational age [AGA] or large for gestational age [LGA]), and birthweight (low birthweight, LBW [<2500 g], nonLBW) as ten types (using all three outcomes), six types (by excluding the birthweight categorisation), and four types (by collapsing the AGA and LGA categories). We defined small types as those with at least one classification of LBW, PT or SGA. We presented study characteristics, participant characteristics, data missingness, and prevalence of newborn types by region and study. Results: Among 541 285 live births, 476 939 (88.1%) had non-missing and plausible values for gestational age, birthweight and sex required to construct the newborn types. The median prevalences of ten types across studies were T+AGA+nonLBW (58.0%), T+LGA+nonLBW (3.3%), T+AGA+LBW (0.5%), T+SGA+nonLBW (14.2%), T+SGA+LBW (7.1%), PT+LGA+nonLBW (1.6%), PT+LGA+LBW (0.2%), PT+AGA+nonLBW (3.7%), PT+AGA+LBW (3.6%) and PT+SGA+LBW (1.0%). The median prevalence of small types (six types, 37.6%) varied across studies and within regions and was higher in Southern Asia (52.4%) than in Sub-Saharan Africa (34.9%). Conclusions: Further investigation is needed to describe the mortality risks associated with newborn types and understand the implications of this framework for local targeting of interventions to prevent adverse pregnancy outcomes in LMICs.