The Biosafety Research Road Map: The Search for Evidence to Support Practices in the Laboratory - Shigella spp.
Issued Date
2023-06-01
Resource Type
ISSN
15356760
eISSN
24701246
Scopus ID
2-s2.0-85162242856
Journal Title
Applied Biosafety
Volume
28
Issue
2
Start Page
96
End Page
101
Rights Holder(s)
SCOPUS
Bibliographic Citation
Applied Biosafety Vol.28 No.2 (2023) , 96-101
Suggested Citation
Blacksell S.D., Dhawan S., Kusumoto M., Le K.K., Davis B.J., Summermatter K., O'Keefe J., Kozlovac J., Almuhairi S.S., Sendow I., Scheel C.M., Ahumibe A., Masuku Z.M., Bennett A.M., Kojima K., Harper D.R., Hamilton K. The Biosafety Research Road Map: The Search for Evidence to Support Practices in the Laboratory - Shigella spp.. Applied Biosafety Vol.28 No.2 (2023) , 96-101. 101. doi:10.1089/apb.2022.0046 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/87666
Title
The Biosafety Research Road Map: The Search for Evidence to Support Practices in the Laboratory - Shigella spp.
Author's Affiliation
World Organisation for Animal Health (WOAH)
Badan Riset dan Inovasi Nasional
UK Health Security Agency
Mahidol Oxford Tropical Medicine Research Unit
Nigeria Centre for Disease Control
National Institute for Communicable Diseases
Organisation Mondiale de la Santé
Centers for Disease Control and Prevention
Chatham House
University of Bern
Nuffield Department of Medicine
USDA ARS Beltsville Agricultural Research Center
Abu Dhabi Agriculture and Food Safety Authority
Ministry for Primary Industries
Badan Riset dan Inovasi Nasional
UK Health Security Agency
Mahidol Oxford Tropical Medicine Research Unit
Nigeria Centre for Disease Control
National Institute for Communicable Diseases
Organisation Mondiale de la Santé
Centers for Disease Control and Prevention
Chatham House
University of Bern
Nuffield Department of Medicine
USDA ARS Beltsville Agricultural Research Center
Abu Dhabi Agriculture and Food Safety Authority
Ministry for Primary Industries
Other Contributor(s)
Abstract
Introduction: Shigella bacteria cause shigellosis, a gastrointestinal infection most often acquired from contaminated food or water. Methods: In this review, the general characteristics of Shigella bacteria are described, cases of laboratory-acquired infections (LAIs) are discussed, and evidence gaps in current biosafety practices are identified. Results: LAIs are undoubtedly under-reported. Owing to the low infectious dose, rigorous biosafety level 2 practices are required to prevent LAIs resulting from sample manipulation or contact with infected surfaces. Conclusions: It is recommended that, before laboratory work with Shigella, an evidence-based risk assessment be conducted. Particular emphasis should be placed on personal protective equipment, handwashing, and containment practices for procedures that generate aerosols or droplets.