Isothermal Amplification Technology for Disease Diagnosis
Issued Date
2022-09-01
Resource Type
eISSN
20796374
Scopus ID
2-s2.0-85138361988
Pubmed ID
36140062
Journal Title
Biosensors
Volume
12
Issue
9
Rights Holder(s)
SCOPUS
Bibliographic Citation
Biosensors Vol.12 No.9 (2022)
Suggested Citation
Boonbanjong P., Treerattrakoon K., Waiwinya W., Pitikultham P., Japrung D. Isothermal Amplification Technology for Disease Diagnosis. Biosensors Vol.12 No.9 (2022). doi:10.3390/bios12090677 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/83620
Title
Isothermal Amplification Technology for Disease Diagnosis
Other Contributor(s)
Abstract
Isothermal amplification (IA) is a nucleic acid amplification technology (NAAT) that has contributed significantly to the healthcare system. The combination of NAAT with a suitable detection platform resulted in higher sensitivity, specificity, and rapid disease diagnosis. Traditional NAAT, such as polymerase chain reaction (PCR), is widely applied in the general healthcare system but is rarely accessed in resource-limited hospitals. Some IA methods provide a rapid, sensitive, specific, and simple method for disease diagnosis. However, not all IA techniques have been regularly used in clinical applications because different biomarkers and sample types affect either the enzyme in the IA system or sample preparation. This review focuses on the application of some IA techniques that have been applied in the medical field and have the potential for use at points of care.