Obstructive Sleep Apnea and Sensorineural Hearing Loss: A Systematic Review and Meta-analysis
Issued Date
2022-01-01
Resource Type
ISSN
01945998
eISSN
10976817
Scopus ID
2-s2.0-85138274595
Pubmed ID
36040818
Journal Title
Otolaryngology - Head and Neck Surgery (United States)
Rights Holder(s)
SCOPUS
Bibliographic Citation
Otolaryngology - Head and Neck Surgery (United States) (2022)
Suggested Citation
Kasemsuk N., Chayopasakul V., Banhiran W., Prakairungthong S., Rungmanee S., Suvarnsit K., Atipas S., Keskool P. Obstructive Sleep Apnea and Sensorineural Hearing Loss: A Systematic Review and Meta-analysis. Otolaryngology - Head and Neck Surgery (United States) (2022). doi:10.1177/01945998221120777 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/86291
Title
Obstructive Sleep Apnea and Sensorineural Hearing Loss: A Systematic Review and Meta-analysis
Author's Affiliation
Other Contributor(s)
Abstract
Objectives: To evaluate the associations between obstructive sleep apnea (OSA) and sensorineural hearing loss (SNHL) and the effects of continuous positive airway pressure (CPAP) therapy on SNHL. Data Sources: Ovid Medline, Embase, and Scopus databases. Review Methods: A systematic search was done for studies investigating relationships between OSA and SNHL in adults, with manual searches for additional references. The final update was done on December 22, 2021. The Risk of Bias Assessment Tool for Nonrandomized Studies was applied for quality assessments. Results: The 20 included studies had a total of 34,442 participants (66% male; mean age, 46.6 years). The OSA group had a significantly worse mean hearing threshold level (HTL) than the control group for midfrequency ranges (500, 1000, 2000 Hz; mean difference, 4.00 dB; 95% CI, 2.40-5.61) and high-frequency ranges (4000, 8000 Hz; mean difference, 6.24 dB; 95% CI, 2.99-9.49). An association between OSA and SNHL was found. When compared with controls, patients with OSA had an odds ratio of 1.52 (95% CI, 1.12-2.06) for midfrequency hearing impairment and 1.19 (95% CI, 1.05-1.34) for high-frequency hearing impairment. However, we did not find significant improvements in midfrequency HTL after CPAP therapy. Conclusions: HTL was significantly poorer among participants with OSA (especially in severe cases) than non-OSA controls. Studies on patients with OSA with SNHL treated with CPAP did not show significant improvements in midfrequency HTL. Further studies are warranted on these issues.