Investigating the Dosimetric Leaf Gap Correction Factor of Mobius3D Dose Calculation for Volumetric‑modulated Arc Radiotherapy Plans
Issued Date
2024-01-01
Resource Type
ISSN
09716203
eISSN
19983913
Scopus ID
2-s2.0-85197587489
Journal Title
Journal of Medical Physics
Volume
49
Issue
2
Start Page
261
End Page
269
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Medical Physics Vol.49 No.2 (2024) , 261-269
Suggested Citation
Sawapabmongkon T., Changkaew P., Puttanawarut C., Tangboonduangjit P., Khachonkham S. Investigating the Dosimetric Leaf Gap Correction Factor of Mobius3D Dose Calculation for Volumetric‑modulated Arc Radiotherapy Plans. Journal of Medical Physics Vol.49 No.2 (2024) , 261-269. 269. doi:10.4103/jmp.jmp_11_24 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/99634
Title
Investigating the Dosimetric Leaf Gap Correction Factor of Mobius3D Dose Calculation for Volumetric‑modulated Arc Radiotherapy Plans
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Corresponding Author(s)
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Abstract
Aims: The dosimetric leaf gap (DLG) is a parameter for correcting radiation transmission through the round leaf end of multileaf collimators. The purpose of this study was to determine and investigate the optimal DLG correction factor for 6 MV volumetric-modulated arc radiotherapy (VMAT) plan dose calculations in Mobius3D. Materials and Methods: Seventeen VMAT plans were selected for the DLG correction factor optimization process. The optimal DLG correction factor was defined as the minimum difference between the measured dose and the Mobius3D-calculated dose on the Mobius Verification Phantom™ with different DLG correction factors. Subsequently, the optimal DLG correction factor was applied for Mobius3D dose calculation, and accuracy was assessed by comparing the measured and calculated doses. For verification and validation, the 17 previous plans and 10 newly selected plans underwent Mobius3D calculations with the optimal DLG correction factor, and gamma analysis was performed to compare them to the treatment planning system (TPS). Gamma analysis was also performed between the electronic portal imaging device (EPID) and the TPS for cross-comparison between systems. Results: The DLG correction factor was optimized to −1.252, which reduced the average percentage differences between measured and Mobius3D-calculated doses from 2.23% ±1.21% to 0.03% ±1.82%. The cross-comparison between Mobius3D/TPS and EPID/TPS revealed a similar trend in gamma passing rate (>95%) in both the verification and validation plans. Conclusion: The DLG correction factor strongly influences the accuracy of Mobius3D-calculated doses. Applying the optimal DLG correction factor can increase dose agreement and gamma passing rate between calculation and delivered doses of VMAT plans, which emphasizes the importance of optimizing this factor during the commissioning process.