A Review of Cyclodextrin Encapsulation and Intelligent Response for the Release of Curcumin
10
Issued Date
2022-12-01
Resource Type
eISSN
20734360
Scopus ID
2-s2.0-85144601597
Journal Title
Polymers
Volume
14
Issue
24
Rights Holder(s)
SCOPUS
Bibliographic Citation
Polymers Vol.14 No.24 (2022)
Suggested Citation
Li J., Xu F., Dai Y., Zhang J., Shi Y., Lai D., Sriboonvorakul N., Hu J. A Review of Cyclodextrin Encapsulation and Intelligent Response for the Release of Curcumin. Polymers Vol.14 No.24 (2022). doi:10.3390/polym14245421 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/84137
Title
A Review of Cyclodextrin Encapsulation and Intelligent Response for the Release of Curcumin
Author's Affiliation
Other Contributor(s)
Abstract
To overcome the low water solubility and low bioavailability of curcumin (CUR), multiple delivery strategies have been proposed. Among these, cyclodextrin-based carriers have been widely used for the encapsulation and delivery of CUR. Cyclodextrins (CDs), as natural oligosaccharides, have been well known for their biodegradability, biocompatibility, non-toxicity, and internal hydrophobic and external hydrophilic structural features. This paper summarizes the recently reported CD-based carriers for encapsulating CUR. Particularly, the polymerization properties of CD self-assembly to enhance the encapsulation of CUR are discussed. In addition, the current progress on stimuli-responsive CD carriers for controlled release of CUR is described, which laid an important foundation for the development of CUR-based precision therapy in clinical practice. In conclusion, this review may provide ideas for the future development of a CD-based encapsulant for CUR.