Sex Differences in Complications Following Total Hip Arthroplasty: A Population-Based Study
3
Issued Date
2024-01-01
Resource Type
ISSN
08835403
eISSN
15328406
Scopus ID
2-s2.0-85196547901
Pubmed ID
38797453
Journal Title
Journal of Arthroplasty
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Arthroplasty (2024)
Suggested Citation
Grant S., Pincus D., Ruangsomboon P., Lex J.R., Sheth U., Ravi B. Sex Differences in Complications Following Total Hip Arthroplasty: A Population-Based Study. Journal of Arthroplasty (2024). doi:10.1016/j.arth.2024.05.062 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/99154
Title
Sex Differences in Complications Following Total Hip Arthroplasty: A Population-Based Study
Corresponding Author(s)
Other Contributor(s)
Abstract
Background: The relationship between sex and outcomes, especially complications, after total hip arthroplasty (THA) has not been well established. This study aimed to identify if patient biological sex significantly impacted complications after THA in Ontario, Canada. Methods: A population-based retrospective cohort study of patients undergoing primary THA in Ontario from April 1, 2015 to March 31, 2020 was conducted. The primary outcome was major surgical complications within a year postsurgery (a composite of revision, deep infection requiring surgery, and dislocation). Secondary outcomes included the individual component of the composite primary outcome and major medical complications within 30 days. Proportional hazards regression calculated the adjusted hazards ratio for major surgical complications in men relative to women, adjusting for age, comorbidities, neighborhood income quintile, surgeon and hospital volume, and year of surgery. Results: A total of 67,077 patients (median age 68 years; 54.1% women) from 61 hospitals were included; women were older with a higher prevalence of frailty. Women had a higher rate of major surgical complications within 1 year of surgery compared to men (2.9 versus 2.5%, adjusted odds ratio 1.19, 95% confidence interval 1.08 to 1.33, P = .0009). Conversely, men had a higher risk for medical complications within 30 days (6.3 versus 2.7%, P < .001). Conclusions: Observable sex disparities exist in post-THA complications; women face surgical complications predominantly, while medical complications are more prevalent in men. These insights can shape preoperative patient consultations. Level of Evidence: Level III.