Patient With Probable Invasive Pulmonary Aspergillosis and Idiopathic Bilateral Chylothorax With Chylopericardium May Experience Unachievable Therapeutic Voriconazole Serum Levels

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dc.contributor.authorTharanon V.
dc.contributor.authorMuangkasem A.
dc.contributor.authorInprasit N.
dc.contributor.authorChantharit P.
dc.contributor.correspondenceTharanon V.
dc.contributor.otherMahidol University
dc.date.accessioned2025-05-09T18:19:40Z
dc.date.available2025-05-09T18:19:40Z
dc.date.issued2025-01-01
dc.description.abstractVoriconazole (VRZ) is an effective first-line treatment for invasive pulmonary aspergillosis. This case report aims to describe the unachievable therapeutic VRZ serum levels in a patient with probable invasive pulmonary aspergillosis and idiopathic bilateral chylothorax with chylopericardium requiring intercostal drainage. Moreover, extrahepatic VRZ loss via intercostal drainage was observed by measuring VRZ in the chylous fluid, which was comparable to the serum concentration.
dc.identifier.citationTherapeutic Drug Monitoring (2025)
dc.identifier.doi10.1097/FTD.0000000000001332
dc.identifier.eissn15363694
dc.identifier.issn01634356
dc.identifier.scopus2-s2.0-105003936254
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/123456789/109965
dc.rights.holderSCOPUS
dc.subjectPharmacology, Toxicology and Pharmaceutics
dc.subjectMedicine
dc.titlePatient With Probable Invasive Pulmonary Aspergillosis and Idiopathic Bilateral Chylothorax With Chylopericardium May Experience Unachievable Therapeutic Voriconazole Serum Levels
dc.typeArticle
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=105003936254&origin=inward
oaire.citation.titleTherapeutic Drug Monitoring
oairecerif.author.affiliationRamathibodi Hospital
oairecerif.author.affiliationMahidol University

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