The Biosafety Research Road Map: The Search for Evidence to Support Practices in the Laboratory - SARS-CoV-2
Issued Date
2023-06-01
Resource Type
ISSN
15356760
eISSN
24701246
Scopus ID
2-s2.0-85162194585
Journal Title
Applied Biosafety
Volume
28
Issue
2
Start Page
87
End Page
95
Rights Holder(s)
SCOPUS
Bibliographic Citation
Applied Biosafety Vol.28 No.2 (2023) , 87-95
Suggested Citation
Blacksell S.D., Dhawan S., Kusumoto M., Le K.K., Summermatter K., O'Keefe J., Kozlovac J., Almuhairi S.S., Sendow I., Scheel C.M., Ahumibe A., Masuku Z.M., Kojima K., Harper D.R., Hamilton K. The Biosafety Research Road Map: The Search for Evidence to Support Practices in the Laboratory - SARS-CoV-2. Applied Biosafety Vol.28 No.2 (2023) , 87-95. 95. doi:10.1089/apb.2022.0039 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/87668
Title
The Biosafety Research Road Map: The Search for Evidence to Support Practices in the Laboratory - SARS-CoV-2
Author's Affiliation
World Organisation for Animal Health (WOAH)
Badan Riset dan Inovasi Nasional
Mahidol Oxford Tropical Medicine Research Unit
Nigeria Centre for Disease Control
National Institute for Communicable Diseases
Organisation Mondiale de la Santé
Centers for Disease Control and Prevention
Chatham House
University of Bern
Nuffield Department of Medicine
USDA ARS Beltsville Agricultural Research Center
Abu Dhabi Agriculture and Food Safety Authority
Ministry for Primary Industries
Badan Riset dan Inovasi Nasional
Mahidol Oxford Tropical Medicine Research Unit
Nigeria Centre for Disease Control
National Institute for Communicable Diseases
Organisation Mondiale de la Santé
Centers for Disease Control and Prevention
Chatham House
University of Bern
Nuffield Department of Medicine
USDA ARS Beltsville Agricultural Research Center
Abu Dhabi Agriculture and Food Safety Authority
Ministry for Primary Industries
Other Contributor(s)
Abstract
Introduction: The SARS-CoV-2 virus emerged as a novel virus and is the causative agent of the COVID-19 pandemic. It spreads readily human-to-human through droplets and aerosols. The Biosafety Research Roadmap aims to support the application of laboratory biological risk management by providing an evidence base for biosafety measures. This involves assessing the current biorisk management evidence base, identifying research and capability gaps, and providing recommendations on how an evidence-based approach can support biosafety and biosecurity, including in low-resource settings. Methods: A literature search was conducted to identify potential gaps in biosafety and focused on five main sections, including the route of inoculation/modes of transmission, infectious dose, laboratory-acquired infections, containment releases, and disinfection and decontamination strategies. Results: There are many knowledge gaps related to biosafety and biosecurity due to the SARS-CoV-2 virus's novelty, including infectious dose between variants, personal protective equipment for personnel handling samples while performing rapid diagnostic tests, and laboratory-acquired infections. Detecting vulnerabilities in the biorisk assessment for each agent is essential to contribute to the improvement and development of laboratory biosafety in local and national systems.