Global impact of the COVID-19 pandemic on subarachnoid haemorrhage hospitalisations, aneurysm treatment and in-hospital mortality: 1-year follow-up
Issued Date
2022-10-01
Resource Type
ISSN
00223050
eISSN
1468330X
Scopus ID
2-s2.0-85134306667
Pubmed ID
35902229
Journal Title
Journal of Neurology, Neurosurgery and Psychiatry
Volume
93
Issue
10
Start Page
1028
End Page
1038
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Neurology, Neurosurgery and Psychiatry Vol.93 No.10 (2022) , 1028-1038
Suggested Citation
Nguyen T.N., Qureshi M.M., Klein P., Yamagami H., Mikulik R., Etminan N., Abdalkader M., Mansour O.Y., Czlonkowska A., Lo H., Sathya A., Demeestere J., Tsivgoulis G., Sakai N., Sedova P., Kristoffersen E.S., Mohammaden M., Lereis V.P., Scollo S.D., Ma A., Rahman A., Bonnet T., Cortier J., Raedt S.D., Lemmens R., Ligot N., Hidalgo R.C.T., Cuervo D.L.M., De Oliveira Neves L., Rezende M.T.S., Santiago I.B., Sirakov A., Sirakov S., Cora E.A., Kelly M.E., Lavoie P., Peeling L., Pikula A., Rivera R., Chen H.S., Chen Y., Fang H., Bedekovic M.R., Budincevic H., Strossmayer J.J., Čabal M., Hrabanovska E., Jurak L., Kadlckova J., Karpowicz I., Klečka L., Kovař M., Neumann J., Palouškova H., Reiser M., Rekova P., Škorňa M., Šramek M., Vitkova E., Žakova L., Sobh K., Alpay K., Rautio R., Strbian D., Gentric J.C., Magro E., Naggara O., Reiner P., Abdulazim A., Bohmann F.O., Boskamp S., Gerber J.C., Kaiser D.P.O., Kestner R.I., Mbroh J., Neyazi M., Rosenkranz M., Poli S., Thomalla G., Karapanayiotides T., Kargiotis O., Koutroulou I., Palaiodimou L., Guerra J.D.B., Huded V., Nagendra S., Prajapati C., Krishna A., Sani A.F., Ghoreishi A., Ilkhchi R.B., Jalili J., Sabetay S.I., Raya T.A., Acampa M., Longoni M., Bigliani C.R., Castellan L., Ornello R., Renieri L. Global impact of the COVID-19 pandemic on subarachnoid haemorrhage hospitalisations, aneurysm treatment and in-hospital mortality: 1-year follow-up. Journal of Neurology, Neurosurgery and Psychiatry Vol.93 No.10 (2022) , 1028-1038. 1038. doi:10.1136/jnnp-2022-329200 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/87236
Title
Global impact of the COVID-19 pandemic on subarachnoid haemorrhage hospitalisations, aneurysm treatment and in-hospital mortality: 1-year follow-up
Author(s)
Nguyen T.N.
Qureshi M.M.
Klein P.
Yamagami H.
Mikulik R.
Etminan N.
Abdalkader M.
Mansour O.Y.
Czlonkowska A.
Lo H.
Sathya A.
Demeestere J.
Tsivgoulis G.
Sakai N.
Sedova P.
Kristoffersen E.S.
Mohammaden M.
Lereis V.P.
Scollo S.D.
Ma A.
Rahman A.
Bonnet T.
Cortier J.
Raedt S.D.
Lemmens R.
Ligot N.
Hidalgo R.C.T.
Cuervo D.L.M.
De Oliveira Neves L.
Rezende M.T.S.
Santiago I.B.
Sirakov A.
Sirakov S.
Cora E.A.
Kelly M.E.
Lavoie P.
Peeling L.
Pikula A.
Rivera R.
Chen H.S.
Chen Y.
Fang H.
Bedekovic M.R.
Budincevic H.
Strossmayer J.J.
Čabal M.
Hrabanovska E.
Jurak L.
Kadlckova J.
Karpowicz I.
Klečka L.
Kovař M.
Neumann J.
Palouškova H.
Reiser M.
Rekova P.
Škorňa M.
Šramek M.
Vitkova E.
Žakova L.
Sobh K.
Alpay K.
Rautio R.
Strbian D.
Gentric J.C.
Magro E.
Naggara O.
Reiner P.
Abdulazim A.
Bohmann F.O.
Boskamp S.
Gerber J.C.
Kaiser D.P.O.
Kestner R.I.
Mbroh J.
Neyazi M.
Rosenkranz M.
Poli S.
Thomalla G.
Karapanayiotides T.
Kargiotis O.
Koutroulou I.
Palaiodimou L.
Guerra J.D.B.
Huded V.
Nagendra S.
Prajapati C.
Krishna A.
Sani A.F.
Ghoreishi A.
Ilkhchi R.B.
Jalili J.
Sabetay S.I.
Raya T.A.
Acampa M.
Longoni M.
Bigliani C.R.
Castellan L.
Ornello R.
Renieri L.
Qureshi M.M.
Klein P.
Yamagami H.
Mikulik R.
Etminan N.
Abdalkader M.
Mansour O.Y.
Czlonkowska A.
Lo H.
Sathya A.
Demeestere J.
Tsivgoulis G.
Sakai N.
Sedova P.
Kristoffersen E.S.
Mohammaden M.
Lereis V.P.
Scollo S.D.
Ma A.
Rahman A.
Bonnet T.
Cortier J.
Raedt S.D.
Lemmens R.
Ligot N.
Hidalgo R.C.T.
Cuervo D.L.M.
De Oliveira Neves L.
Rezende M.T.S.
Santiago I.B.
Sirakov A.
Sirakov S.
Cora E.A.
Kelly M.E.
Lavoie P.
Peeling L.
Pikula A.
Rivera R.
Chen H.S.
Chen Y.
Fang H.
Bedekovic M.R.
Budincevic H.
Strossmayer J.J.
Čabal M.
Hrabanovska E.
Jurak L.
Kadlckova J.
Karpowicz I.
Klečka L.
Kovař M.
Neumann J.
Palouškova H.
Reiser M.
Rekova P.
Škorňa M.
Šramek M.
Vitkova E.
Žakova L.
Sobh K.
Alpay K.
Rautio R.
Strbian D.
Gentric J.C.
Magro E.
Naggara O.
Reiner P.
Abdulazim A.
Bohmann F.O.
Boskamp S.
Gerber J.C.
Kaiser D.P.O.
Kestner R.I.
Mbroh J.
Neyazi M.
Rosenkranz M.
Poli S.
Thomalla G.
Karapanayiotides T.
Kargiotis O.
Koutroulou I.
Palaiodimou L.
Guerra J.D.B.
Huded V.
Nagendra S.
Prajapati C.
Krishna A.
Sani A.F.
Ghoreishi A.
Ilkhchi R.B.
Jalili J.
Sabetay S.I.
Raya T.A.
Acampa M.
Longoni M.
Bigliani C.R.
Castellan L.
Ornello R.
Renieri L.
Author's Affiliation
Mazumdar Shaw Medical Center
Universitätsklinikum Carl Gustav Carus Dresden
Imam Reza General Hospital
Vali-e-Asr Hospital, Zanjan University of Medical Sciences (ZUMS)
Université Paris Cité
IRCCS San Martino Polyclinic Hospital
Kobe City Medical Center General Hospital
Hertie-Institut für klinische Hirnforschung
Krajská nemocnice Liberec, a.s.
CHU de Québec - Université Laval
Shenyang General Hospital of PLA
Institute of Psychiatry and Neurology, Warszawa
Universitair Ziekenhuis Brussel
Universitas Udayana
Universitas Airlangga
Hospital Moinhos de Vento
Fakultní Nemocnice u Sv. Anny v Brně
Akershus University Hospital
Hôpital Erasme
Hospital de Base
Všeobecná Fakultní Nemocnice v Praze
National Hospital Organization Osaka National Hospital
Grant Medical College
Albertinen in Besten Händen
Tabriz University of Medical Sciences
KU Leuven– University Hospital Leuven
Hillel Yaffe Medical Center
University General Hospital of Thessaloniki "AHEPA"
Turun Yliopistollinen Keskussairaala
Fundacion Para La Lucha Contra Las Enfermedades Neurologicas de La Infancia
General Hospital Sveti Duh
Fakultni Nemocnice Brno
Azienda Ospedaliera Careggi
Faculty of Medicine
Metropolitan Hospital, Athens
Università degli Studi dell'Aquila
Royal University Hospital
Sveučilište Josipa Jurja Strossmayera u Osijeku
Technische Universität Dresden
Prague Central Military Hospital
Eberhard Karls Universität Tübingen
Helsinki University Hospital
University of Toronto
Charles University
Dalhousie University
Ospedale M. Bufalini
Attikon University Hospital
Na Homolce Hospital
Universitätsklinikum Frankfurt
Goethe-Universität Frankfurt am Main
Royal North Shore Hospital
Boston University School of Medicine
Universitätsklinikum Hamburg-Eppendorf
Centre Hospitalier Universitaire de Brest
Sir Salimullah Medical College
Boston Medical Center
Università degli Studi di Siena
Emory University School of Medicine
Universitätsklinikum Mannheim
Hospital J.M. Ramos Mejia, Buenos Aires
El Hussein Alzahar University Hospital
Uherskohradišt'Ska Hospital
Sestre Milosrdnice University Hospital Center
Foshan Sanshui District People's Hospital
a.s. – Nemocnice Chomutov
Nemocnice Třinec
Hospital Vyskov
Lariboisière
Hospital General San Juan de Dios
University Hospital Saint Ivan Rilski
Karvina Mining Hospital
São Carlos Hospital
Hospital Karlovy Vary
Instituto de Neurocirugía Dr. Asenjo
Hospital Belo Horizonte
Hospital České Budějovice
Faculty Hospital Ostrava
Universitätsklinikum Carl Gustav Carus Dresden
Imam Reza General Hospital
Vali-e-Asr Hospital, Zanjan University of Medical Sciences (ZUMS)
Université Paris Cité
IRCCS San Martino Polyclinic Hospital
Kobe City Medical Center General Hospital
Hertie-Institut für klinische Hirnforschung
Krajská nemocnice Liberec, a.s.
CHU de Québec - Université Laval
Shenyang General Hospital of PLA
Institute of Psychiatry and Neurology, Warszawa
Universitair Ziekenhuis Brussel
Universitas Udayana
Universitas Airlangga
Hospital Moinhos de Vento
Fakultní Nemocnice u Sv. Anny v Brně
Akershus University Hospital
Hôpital Erasme
Hospital de Base
Všeobecná Fakultní Nemocnice v Praze
National Hospital Organization Osaka National Hospital
Grant Medical College
Albertinen in Besten Händen
Tabriz University of Medical Sciences
KU Leuven– University Hospital Leuven
Hillel Yaffe Medical Center
University General Hospital of Thessaloniki "AHEPA"
Turun Yliopistollinen Keskussairaala
Fundacion Para La Lucha Contra Las Enfermedades Neurologicas de La Infancia
General Hospital Sveti Duh
Fakultni Nemocnice Brno
Azienda Ospedaliera Careggi
Faculty of Medicine
Metropolitan Hospital, Athens
Università degli Studi dell'Aquila
Royal University Hospital
Sveučilište Josipa Jurja Strossmayera u Osijeku
Technische Universität Dresden
Prague Central Military Hospital
Eberhard Karls Universität Tübingen
Helsinki University Hospital
University of Toronto
Charles University
Dalhousie University
Ospedale M. Bufalini
Attikon University Hospital
Na Homolce Hospital
Universitätsklinikum Frankfurt
Goethe-Universität Frankfurt am Main
Royal North Shore Hospital
Boston University School of Medicine
Universitätsklinikum Hamburg-Eppendorf
Centre Hospitalier Universitaire de Brest
Sir Salimullah Medical College
Boston Medical Center
Università degli Studi di Siena
Emory University School of Medicine
Universitätsklinikum Mannheim
Hospital J.M. Ramos Mejia, Buenos Aires
El Hussein Alzahar University Hospital
Uherskohradišt'Ska Hospital
Sestre Milosrdnice University Hospital Center
Foshan Sanshui District People's Hospital
a.s. – Nemocnice Chomutov
Nemocnice Třinec
Hospital Vyskov
Lariboisière
Hospital General San Juan de Dios
University Hospital Saint Ivan Rilski
Karvina Mining Hospital
São Carlos Hospital
Hospital Karlovy Vary
Instituto de Neurocirugía Dr. Asenjo
Hospital Belo Horizonte
Hospital České Budějovice
Faculty Hospital Ostrava
Other Contributor(s)
Abstract
Background Prior studies indicated a decrease in the incidences of aneurysmal subarachnoid haemorrhage (aSAH) during the early stages of the COVID-19 pandemic. We evaluated differences in the incidence, severity of aSAH presentation, and ruptured aneurysm treatment modality during the first year of the COVID-19 pandemic compared with the preceding year. Methods We conducted a cross-sectional study including 49 countries and 187 centres. We recorded volumes for COVID-19 hospitalisations, aSAH hospitalisations, Hunt-Hess grade, coiling, clipping and aSAH in-hospital mortality. Diagnoses were identified by International Classification of Diseases, 10th Revision, codes or stroke databases from January 2019 to May 2021. Results Over the study period, there were 16 247 aSAH admissions, 344 491 COVID-19 admissions, 8300 ruptured aneurysm coiling and 4240 ruptured aneurysm clipping procedures. Declines were observed in aSAH admissions (-6.4% (95% CI-7.0% to-5.8%), p=0.0001) during the first year of the pandemic compared with the prior year, most pronounced in high-volume SAH and high-volume COVID-19 hospitals. There was a trend towards a decline in mild and moderate presentations of subarachnoid haemorrhage (SAH) (mild:-5% (95% CI-5.9% to-4.3%), p=0.06; moderate:-8.3% (95% CI-10.2% to-6.7%), p=0.06) but no difference in higher SAH severity. The ruptured aneurysm clipping rate remained unchanged (30.7% vs 31.2%, p=0.58), whereas ruptured aneurysm coiling increased (53.97% vs 56.5%, p=0.009). There was no difference in aSAH in-hospital mortality rate (19.1% vs 20.1%, p=0.12). Conclusion During the first year of the pandemic, there was a decrease in aSAH admissions volume, driven by a decrease in mild to moderate presentation of aSAH. There was an increase in the ruptured aneurysm coiling rate but neither change in the ruptured aneurysm clipping rate nor change in aSAH in-hospital mortality. Trial registration number NCT04934020.