Synergistic Anti-Pathogenic/Photocatalytic Efficacy of Cymbopogon Flexuosus-Mediated Silver Nanoparticles in Complex Paradigm for One Health Resilience

Abstract

Antipathogenic strategies are radical vectors in symptomatic treatment and averting morbidity of high-risk contagious contributing to the complex paradigm of one health management. This study investigates the physicochemical attributes and antimicrobial activities in synergy with the photocatalytic efficacy of biogenic silver nanoparticles (AgNPs). Biogenic AgNPs were engineered using an economical and eco-friendly route employing the Lemongrass’s essential oil as a multifunctional reducing, capping, stabilizing, and doping agent. Structural and morphological outcomes reveal the formation of crystalline spherical AgNPs with a size of 7 to 30 nm. Fabricated AgNPs exhibited broadband antibacterial (against Bacillus subtilis and Escherichia coli) potencies comparable to state-of-the-art antipathogenic drugs utilized for treating infectious disorders. Besides, engineered biogenic AgNPs demonstrated excellent photocatalytic degradation effectiveness of roughly 96.63% towards methylene blue (MB) in Sunlight for 2 h without the use of an external reducing agent. Moreover, the biogenic AgNPs open new windows to tackle the prominent issues of antimicrobial resistance and greener dye removal causative to sustainable water health management. Based on the exceptional results, imperative from a biocompatible, non-toxic, eco-friendly, and economic perspective, such essential oil -mediated AgNPs are novel nanoplatforms for broadband one health applications.