Vitamin D and Visceral Obesity in Humans: What Should Clinicians Know?
Issued Date
2022-08-01
Resource Type
eISSN
20726643
Scopus ID
2-s2.0-85135135415
Pubmed ID
35893929
Journal Title
Nutrients
Volume
14
Issue
15
Rights Holder(s)
SCOPUS
Bibliographic Citation
Nutrients Vol.14 No.15 (2022)
Suggested Citation
Chattranukulchai Shantavasinkul P., Nimitphong H. Vitamin D and Visceral Obesity in Humans: What Should Clinicians Know?. Nutrients Vol.14 No.15 (2022). doi:10.3390/nu14153075 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/83175
Title
Vitamin D and Visceral Obesity in Humans: What Should Clinicians Know?
Author's Affiliation
Other Contributor(s)
Abstract
The extraskeletal effect of vitamin D on adipose tissue biology and modulation in human obesity is of great interest and has been extensively investigated. Current evidence from preclinical and clinical studies in human adipose tissue suggests that the anti-inflammatory effects of vitamin D are evident and consistent, whereas the effects of vitamin D on adipocyte differentiation, adipogenesis, and energy metabolism and the effects of vitamin D supplementation on adipokine levels are inconclusive. Interventional studies related to medical and surgical weight loss in humans have shown small or no improvement in vitamin D status. Additionally, the benefit of vitamin D supplementation for the reduction in visceral adipose tissue has only been demonstrated in a few studies. Overall, the findings on the relationship between vitamin D and visceral adipose tissue in humans are still inconclusive. Further studies are required to confirm the beneficial effects of vitamin D on ameliorating adipose tissue dysfunction.