Swellable microneedles for nitrate detection in food
Issued Date
2022-01-01
Resource Type
eISSN
22147853
Scopus ID
2-s2.0-85137394889
Journal Title
Materials Today: Proceedings
Volume
66
Start Page
3191
End Page
3197
Rights Holder(s)
SCOPUS
Bibliographic Citation
Materials Today: Proceedings Vol.66 (2022) , 3191-3197
Suggested Citation
Sumontha T., Veeraphan P., Leelawattanachai J., Triampo D. Swellable microneedles for nitrate detection in food. Materials Today: Proceedings Vol.66 (2022) , 3191-3197. 3197. doi:10.1016/j.matpr.2022.08.224 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/85098
Title
Swellable microneedles for nitrate detection in food
Author(s)
Author's Affiliation
Other Contributor(s)
Abstract
Nitrate is used as a food additive to preserve meat and extend shelf-life. Nitrate inhibits microorganisms that cause spoilage. Epidemiological research has been reported that high nitrate dietary intakes are associated with gastric cancer, bladder cancer, and pancreatic cancer. This study aims to detect nitrate in food using swellable microneedles. The swellable microneedles were developed based on poly(methyl vinyl ether-alt-maleic acid) (PMVE/MA) and poly(ethylene glycol) (PEG) and incorporated with colorimetric paper for nitrate detection. Our data demonstrated the microneedles could absorb liquid containing sodium nitrate and reacted with the reagents in the test strip on the microneedles. The detection limit of this microneedle-based technique is 500 ppm which is the cutoff level of nitrate permitted to be used in food by the Ministry of Public Health of Thailand. This developed technique requires only one step of sample preparation.