Characteristics of Hospital-Acquired Respiratory Syncytial Virus (RSV) Infection in Young Children Prior to the COVID-19 Outbreak
Issued Date
2023-01-01
Resource Type
ISSN
01252208
Scopus ID
2-s2.0-85179620906
Journal Title
Journal of the Medical Association of Thailand
Volume
106
Issue
11
Start Page
1034
End Page
1040
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of the Medical Association of Thailand Vol.106 No.11 (2023) , 1034-1040
Suggested Citation
Ruenglerdpong S., Lapphra K., Phongsamart W., Wittawatmongkol O., Rungmaitree S., Sitthirit W., Sinderadard K., Chokephaibulkit K. Characteristics of Hospital-Acquired Respiratory Syncytial Virus (RSV) Infection in Young Children Prior to the COVID-19 Outbreak. Journal of the Medical Association of Thailand Vol.106 No.11 (2023) , 1034-1040. 1040. doi:10.35755/jmedassocthai.2023.11.13911 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/95583
Title
Characteristics of Hospital-Acquired Respiratory Syncytial Virus (RSV) Infection in Young Children Prior to the COVID-19 Outbreak
Author's Affiliation
Corresponding Author(s)
Other Contributor(s)
Abstract
Background: Respiratory syncytial virus (RSV) causes healthcare-associated respiratory infections in pediatric patients. Previous studies in developed countries have identified risk factors associated with hospital-acquired RSV (HA-RSV) infection. Those risk factors have a higher mortality rate than the risk factors of community-acquired RSV (CA-RSV) infection. Objective: To investigate risk factors, clinical characteristics, and outcomes of RSV infection in young children within hospitals. Materials and Methods: Data from Siriraj Hospital’s surveillance system between 2014 and 2018 was used to include children under five with laboratory-confirmed HA-RSV infection. Two control groups were formed, the CA-RSV infection and non-RSV hospital-acquired infections (non-RSV HAI), which were time-matched with the study group as a 1:2 ratio. Results: Fifty-one HA-RSV cases were identified, with the highest infection rate during the rainy season, which was July to December. HA-RSV patients had higher rates of underlying neuromuscular disease and malignancy. Fever was common in HA-RSV, while upper respiratory and gastrointestinal symptoms were less frequent than CA-RSV. Antibiotic and oseltamivir treatment did not differ significantly. HA-RSV patients had longer stays in the intensive care unit and hospital, but transfer rates and mortality did not differ significantly among the groups. Conclusion: HA-RSV coincides with community outbreaks, being more severe and affecting vulnerable patients. Targeted surveillance during high RSV seasons is crucial for prevention in hospitals.