Diagnostic Modalities in Detecting Cardiovascular Complications of Thalassemia
Issued Date
2022-08-01
Resource Type
ISSN
15306550
eISSN
21538174
Scopus ID
2-s2.0-85135935363
Journal Title
Reviews in Cardiovascular Medicine
Volume
23
Issue
8
Rights Holder(s)
SCOPUS
Bibliographic Citation
Reviews in Cardiovascular Medicine Vol.23 No.8 (2022)
Suggested Citation
Fianza P.I., Pramono A.A., Ghozali M., Sihite T.A., Setiabudi D., Syamsunarno M.R.A.A., Fucharoen S., Panigoro R. Diagnostic Modalities in Detecting Cardiovascular Complications of Thalassemia. Reviews in Cardiovascular Medicine Vol.23 No.8 (2022). doi:10.31083/j.rcm2308267 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/85659
Title
Diagnostic Modalities in Detecting Cardiovascular Complications of Thalassemia
Author's Affiliation
Other Contributor(s)
Abstract
Thalassemia major is the most common monogenetic disorder worldwide, manifested as chronic hemolytic anemia. This condition leads to the need for chronic blood transfusion to be monitored for an iron overload that may be stored in several tissues and organs, including cardiomyocytes, that might cause a broad spectrum of cardiac iron toxicities such as heart failure conduction delays, myocarditis, and arrhythmias. Non-invasive imaging modalities have their benefits and limitations. Each modality complements and generates a comprehensive diagnostic and monitoring of cardiac siderosis in thalassemia major patients.