A review on benefits of quercetin in hyperuricemia and gouty arthritis
Issued Date
2022-07-01
Resource Type
ISSN
13190164
Scopus ID
2-s2.0-85130321650
Journal Title
Saudi Pharmaceutical Journal
Volume
30
Issue
7
Start Page
918
End Page
926
Rights Holder(s)
SCOPUS
Bibliographic Citation
Saudi Pharmaceutical Journal Vol.30 No.7 (2022) , 918-926
Suggested Citation
Nutmakul T. A review on benefits of quercetin in hyperuricemia and gouty arthritis. Saudi Pharmaceutical Journal Vol.30 No.7 (2022) , 918-926. 926. doi:10.1016/j.jsps.2022.04.013 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/86852
Title
A review on benefits of quercetin in hyperuricemia and gouty arthritis
Author(s)
Author's Affiliation
Other Contributor(s)
Abstract
Hyperuricemia becomes a public health problem worldwide. It is not only a major risk factor for gout but also associated with the development of life-threatening diseases such as chronic kidney disease and cardiovascular diseases. Although there are several available therapeutic drugs, some serious adverse effects and contraindications are concerned. These drive the search for an alternative therapy that is effective and safe. Quercetin is of particular interesting since it has been reported numerous pharmacological activities, especially anti-hyperuricemia, antioxidant, anti-inflammation and amelioration of metabolic syndromes and cardiovascular diseases which are comorbidities of hyperuricemia and gout. In addition, quercetin has been widely used as a health supplement for many diseases however, the use for hyperuricemia and gout has not been indicated. Therefore, this review aims to gather and summarize published data regarding the efficacy in preclinical and clinical studies along with possible mechanism of action, and safety aspect of quercetin in order to support the use of quercetin as a dietary supplement for prevention and management of hyperuricemia and gouty arthritis and/or use as alternative or combination therapy to minimize the side effects of the conventional drugs.