Acute Pancreatitis in Childhood: A 10-Year Experience From A Thai University Surgical Center
Issued Date
2022-08-01
Resource Type
ISSN
08853177
eISSN
15364828
Scopus ID
2-s2.0-85142138631
Pubmed ID
36395407
Journal Title
Pancreas
Volume
51
Issue
7
Start Page
808
End Page
813
Rights Holder(s)
SCOPUS
Bibliographic Citation
Pancreas Vol.51 No.7 (2022) , 808-813
Suggested Citation
Boonthai A., Tanpowpong P., Puttanapitak C., Aeesoa S., Losty P.D., Molagool S. Acute Pancreatitis in Childhood: A 10-Year Experience From A Thai University Surgical Center. Pancreas Vol.51 No.7 (2022) , 808-813. 813. doi:10.1097/MPA.0000000000002109 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/83637
Title
Acute Pancreatitis in Childhood: A 10-Year Experience From A Thai University Surgical Center
Other Contributor(s)
Abstract
Objectives This study aimed to describe etiology, management, and health outcomes of children developing acute pancreatitis at a tertiary Thailand pediatric surgery center. Methods Medical case records of all index cases during 2006-2016 were analyzed and reported. Results There were 42 male and 37 female patients, with a mean (standard deviation) age of 10.4 (4.5) years, included in the study. Medications were the commonest etiology for 39.3% of acute pancreatitis attacks, 11.4% for biliary tract disease cases, and 8% for postinterventional studies. In 30% of cases, no cause(s) was defined. Sixty-two patients (78.5%) had elevated serum lipase on hospital admission, whereas only 30.4% showed a raised amylase. Hospital stay was 15 days (interquartile range, 6-27 days). Two major complications in the series were pseudocysts (8.8%) and necrotizing pancreatitis (7.6%). Etiological factors and/or antibiotics were not directly linked to any specific complications. Seventeen children (22.8%) had 1 recurrent episode of acute pancreatitis documented. Mortality rate in index cases was 28%, with a higher percentage harboring a preexisting illness (34.4% vs 5.6%; P = 0.01) and in male than in female patients (41% vs 14%; P = 0.01). Conclusions Deaths from pediatric acute pancreatitis are more prevalent in male individuals and those with a preexisting illness. Targeted strategies aimed at "highest-risk"patients may potentially offset mortality.
