Cancer and fertility management: FIGO best practice advice
Issued Date
2025-01-01
Resource Type
ISSN
00207292
eISSN
18793479
Scopus ID
2-s2.0-105013803299
Pubmed ID
40739998
Journal Title
International Journal of Gynecology and Obstetrics
Rights Holder(s)
SCOPUS
Bibliographic Citation
International Journal of Gynecology and Obstetrics (2025)
Suggested Citation
Purandare N., Ruiloba F., Nguyen-Hoang L., Wilailak S., Yanaihara N., Chung J.P.W., Malhotra J., Mocanu E., Amant F., McNally O., Peters I., Flynn K., El Helali A., Maxwell C., Adam S., Bergman L., Nanda S., Guinto V.T., McAuliffe F.M., Nelson-Piercy C., Nana M., Smith G., Berek J., O'Reilly S., O'Brien P., Jacobsson B., Poon L.C. Cancer and fertility management: FIGO best practice advice. International Journal of Gynecology and Obstetrics (2025). doi:10.1002/ijgo.70426 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/111896
Title
Cancer and fertility management: FIGO best practice advice
Author(s)
Purandare N.
Ruiloba F.
Nguyen-Hoang L.
Wilailak S.
Yanaihara N.
Chung J.P.W.
Malhotra J.
Mocanu E.
Amant F.
McNally O.
Peters I.
Flynn K.
El Helali A.
Maxwell C.
Adam S.
Bergman L.
Nanda S.
Guinto V.T.
McAuliffe F.M.
Nelson-Piercy C.
Nana M.
Smith G.
Berek J.
O'Reilly S.
O'Brien P.
Jacobsson B.
Poon L.C.
Ruiloba F.
Nguyen-Hoang L.
Wilailak S.
Yanaihara N.
Chung J.P.W.
Malhotra J.
Mocanu E.
Amant F.
McNally O.
Peters I.
Flynn K.
El Helali A.
Maxwell C.
Adam S.
Bergman L.
Nanda S.
Guinto V.T.
McAuliffe F.M.
Nelson-Piercy C.
Nana M.
Smith G.
Berek J.
O'Reilly S.
O'Brien P.
Jacobsson B.
Poon L.C.
Author's Affiliation
University of Melbourne
King's College London
The University of Hong Kong
Chinese University of Hong Kong
Queen’s University
University College Dublin
KU Leuven– University Hospital Leuven
Sahlgrenska Universitetssjukhuset
Sahlgrenska Akademin
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Stanford Healthcare
Guy's and St Thomas' NHS Foundation Trust
The Jikei University School of Medicine
King's College Hospital
University College London Hospitals NHS Foundation Trust
Folkehelseinstituttet
Ramathibodi Hospital
Women's College Hospital
University of the Philippines Manila
University Hospital Galway
Faculty of Health Sciences
The Rotunda Hospital Dublin
Asian Hospital and Medical Center, Muntinlupa
Rainbow IVF
Tam Anh General Hospital
St. Luke’s Medical Center Global City
King's College London
The University of Hong Kong
Chinese University of Hong Kong
Queen’s University
University College Dublin
KU Leuven– University Hospital Leuven
Sahlgrenska Universitetssjukhuset
Sahlgrenska Akademin
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Stanford Healthcare
Guy's and St Thomas' NHS Foundation Trust
The Jikei University School of Medicine
King's College Hospital
University College London Hospitals NHS Foundation Trust
Folkehelseinstituttet
Ramathibodi Hospital
Women's College Hospital
University of the Philippines Manila
University Hospital Galway
Faculty of Health Sciences
The Rotunda Hospital Dublin
Asian Hospital and Medical Center, Muntinlupa
Rainbow IVF
Tam Anh General Hospital
St. Luke’s Medical Center Global City
Corresponding Author(s)
Other Contributor(s)
Abstract
Cancer diagnoses in patients of reproductive age require balancing urgent oncological treatment with the need to preserve fertility. This FIGO Best Practice Advice outlines key considerations for fertility management in this population given the rising cancer incidence among young women and the reproductive risks posed by cancer treatments. The guidance evaluates the impact of chemotherapy, radiotherapy, surgery, and emerging therapies—such as targeted agents and immunotherapies—on gonadal function and fertility. Established fertility preservation methods, including oocyte/embryo cryopreservation, sperm banking, and ovarian tissue freezing, are detailed alongside barriers to their adoption, such as cost and limited access. Early collaborative counseling with oncologists and fertility specialists is central to addressing timelines, psychological impacts, and priorities. Post-treatment pathways, including assisted reproduction and surrogacy, are also explored. The guidance stresses the importance of integrating fertility-sparing interventions and fertility preservation into cancer care while advocating for equitable access to resources. Further research is needed to refine preventive interventions, evaluate long-term outcomes, and expand options for survivors globally. By prioritizing fertility preservation within oncological care, healthcare providers can better support the holistic needs of young individuals facing cancer.