Cellular interaction with sericin: a basis for noncommunicable and infectious diseases
Issued Date
2023-01-01
Resource Type
Scopus ID
2-s2.0-85189998823
Journal Title
Silk-Based Biomaterials for Tissue Engineering, Regenerative, and Precision Medicine, 2nd Edition
Start Page
653
End Page
688
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SCOPUS
Bibliographic Citation
Silk-Based Biomaterials for Tissue Engineering, Regenerative, and Precision Medicine, 2nd Edition (2023) , 653-688
Suggested Citation
Wattanavijitkul T., Jantaravinid J., Ampawong S., Aramwit P. Cellular interaction with sericin: a basis for noncommunicable and infectious diseases. Silk-Based Biomaterials for Tissue Engineering, Regenerative, and Precision Medicine, 2nd Edition (2023) , 653-688. 688. doi:10.1016/B978-0-323-96017-5.00020-0 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/97999
Title
Cellular interaction with sericin: a basis for noncommunicable and infectious diseases
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Corresponding Author(s)
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Abstract
In vivo or clinical application inclusion of polymers from both synthetic and biological sources, as evident in biomedical applications such as drug delivery and tissue engineering, introduces interaction with the host immune system. Such an issue is of primary significance and requires crucial thinking before application. Unfortunately, cases are encountered when materials with excellent physical, mechanical, and biological activities are rejected from the studies based on their immunological responses, as evident in allergic and inflammatory manifestation that can lead to treatment failure. Therefore, it is essential for the innate immune responses to any biomaterials to be thoroughly investigated as critical criteria for their potential applications. As a protein, silk sericin, is likely to be an immunological activator or initiates cellular interaction. This chapter discusses the cellular and molecular mechanism of sericin on noncommunicable and infectious diseases.