A 62-Year-Old-Man With Severe Daytime Sleepiness After Primary Central Nervous System Lymphoma
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Issued Date
2026-02-01
Resource Type
ISSN
00123692
eISSN
19313543
Scopus ID
2-s2.0-105028685140
Journal Title
Chest
Volume
169
Issue
2
Start Page
e55
End Page
e60
Rights Holder(s)
SCOPUS
Bibliographic Citation
Chest Vol.169 No.2 (2026) , e55-e60
Suggested Citation
Srikajon J., Tripipitsiriwat A., Orr J.E. A 62-Year-Old-Man With Severe Daytime Sleepiness After Primary Central Nervous System Lymphoma. Chest Vol.169 No.2 (2026) , e55-e60. e60. doi:10.1016/j.chest.2025.08.017 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/114773
Title
A 62-Year-Old-Man With Severe Daytime Sleepiness After Primary Central Nervous System Lymphoma
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Author's Affiliation
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Abstract
Case Presentation: A 62-year-old man with a history of primary central nervous system lymphoma first presented with diplopia, diagnosed 2 years ago. A brain MRI showed multiple solid enhancing mass lesions located at the midline bilateral dorsal medulla to both cervicomedullary junction and right flocculus with edema of the ventrolateral medulla. The brain biopsy confirmed relapsed diffuse large B cell lymphoma. Remission was achieved after a course of high-dose methotrexate, rituximab, and whole-brain radiotherapy. He was referred to the sleep clinic because of snoring, witnessed apnea, and severe daytime sleepiness. He had no dyspnea, cough, or history of aspiration pneumonia. Medications included levetiracetam and midodrine.