Family History and Solar Insolation in Bipolar I Disorder
Issued Date
2026-04-01
Resource Type
ISSN
0001690X
eISSN
16000447
Scopus ID
2-s2.0-105031811696
Pubmed ID
41734899
Journal Title
Acta Psychiatrica Scandinavica
Volume
153
Issue
4
Start Page
270
End Page
278
Rights Holder(s)
SCOPUS
Bibliographic Citation
Acta Psychiatrica Scandinavica Vol.153 No.4 (2026) , 270-278
Suggested Citation
Bauer M., Glenn T., Achtyes E.D., Alda M., Agaoglu E., Altınbaş K., Andreassen O.A., Angelopoulos E., Ardau R., Aydin M., Ayhan Y., Baethge C., Bauer R., Baune B.T., Balaban C., Becerra-Palars C., Behere A.P., Belete H., Belete T., Belizario G.O., Bellivier F., Belmaker R.H., Benedetti F., Berk M., Bersudsky Y., Bicakci, Birabwa-Oketcho H., Bjella T.D., Brady C., Cabrera J., Cappucciati M., Castro A.M.P., Chen W., Cheung E.Y.W., Chiesa S., Chanopoulou M., Crowe M., Cuomo A., Dallaspezia S., Desai P., Dodd S., Etain B., Fagiolini A., Fellendorf F.T., Ferensztajn-Rochowiak E., Fiedorowicz J.G., Fountoulakis K.N., Frye M.A., Geoffroy P.A., Gitlin M.J., Gonzalez-Pinto A., Gottlieb J.F., Grof P., Haarman B.C.M., Harima H., Hasse-Sousa M., Henry C., Hoffding L., Houenou J., Imbesi M., Isometsä E.T., Ivkovic M., Janno S., Johnsen S., Kapczinski F., Karakatsoulis G.N., Kardell M., Kessing L.V., Kim S.J., König B., Kot T.L., Koval M., Kunz M., Lafer B., Landén M., Larsen E.R., Licht R.W., Ludwig V.M., Lopez-Jaramillo C., MacKenzie A., Madsen H.Ø., Madsen S.A.K.A., Mahadevan J., Mahardika A., Mahfoudh K., Manchia M., Marsh W., Martinez-Cengotitabengoa M., Martini J., Martiny K., Mashima Y., McLoughlin D.M., Meesters A.N.R., Meesters Y., Melle I., Meza-Urzúa F., Michaelis E., Mikolas P., Mok Y.M., Monteith S. Family History and Solar Insolation in Bipolar I Disorder. Acta Psychiatrica Scandinavica Vol.153 No.4 (2026) , 270-278. 278. doi:10.1111/acps.70075 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/115698
Title
Family History and Solar Insolation in Bipolar I Disorder
Author(s)
Bauer M.
Glenn T.
Achtyes E.D.
Alda M.
Agaoglu E.
Altınbaş K.
Andreassen O.A.
Angelopoulos E.
Ardau R.
Aydin M.
Ayhan Y.
Baethge C.
Bauer R.
Baune B.T.
Balaban C.
Becerra-Palars C.
Behere A.P.
Belete H.
Belete T.
Belizario G.O.
Bellivier F.
Belmaker R.H.
Benedetti F.
Berk M.
Bersudsky Y.
Bicakci
Birabwa-Oketcho H.
Bjella T.D.
Brady C.
Cabrera J.
Cappucciati M.
Castro A.M.P.
Chen W.
Cheung E.Y.W.
Chiesa S.
Chanopoulou M.
Crowe M.
Cuomo A.
Dallaspezia S.
Desai P.
Dodd S.
Etain B.
Fagiolini A.
Fellendorf F.T.
Ferensztajn-Rochowiak E.
Fiedorowicz J.G.
Fountoulakis K.N.
Frye M.A.
Geoffroy P.A.
Gitlin M.J.
Gonzalez-Pinto A.
Gottlieb J.F.
Grof P.
Haarman B.C.M.
Harima H.
Hasse-Sousa M.
Henry C.
Hoffding L.
Houenou J.
Imbesi M.
Isometsä E.T.
Ivkovic M.
Janno S.
Johnsen S.
Kapczinski F.
Karakatsoulis G.N.
Kardell M.
Kessing L.V.
Kim S.J.
König B.
Kot T.L.
Koval M.
Kunz M.
Lafer B.
Landén M.
Larsen E.R.
Licht R.W.
Ludwig V.M.
Lopez-Jaramillo C.
MacKenzie A.
Madsen H.Ø.
Madsen S.A.K.A.
Mahadevan J.
Mahardika A.
Mahfoudh K.
Manchia M.
Marsh W.
Martinez-Cengotitabengoa M.
Martini J.
Martiny K.
Mashima Y.
McLoughlin D.M.
Meesters A.N.R.
Meesters Y.
Melle I.
Meza-Urzúa F.
Michaelis E.
Mikolas P.
Mok Y.M.
Monteith S.
Glenn T.
Achtyes E.D.
Alda M.
Agaoglu E.
Altınbaş K.
Andreassen O.A.
Angelopoulos E.
Ardau R.
Aydin M.
Ayhan Y.
Baethge C.
Bauer R.
Baune B.T.
Balaban C.
Becerra-Palars C.
Behere A.P.
Belete H.
Belete T.
Belizario G.O.
Bellivier F.
Belmaker R.H.
Benedetti F.
Berk M.
Bersudsky Y.
Bicakci
Birabwa-Oketcho H.
Bjella T.D.
Brady C.
Cabrera J.
Cappucciati M.
Castro A.M.P.
Chen W.
Cheung E.Y.W.
Chiesa S.
Chanopoulou M.
Crowe M.
Cuomo A.
Dallaspezia S.
Desai P.
Dodd S.
Etain B.
Fagiolini A.
Fellendorf F.T.
Ferensztajn-Rochowiak E.
Fiedorowicz J.G.
Fountoulakis K.N.
Frye M.A.
Geoffroy P.A.
Gitlin M.J.
Gonzalez-Pinto A.
Gottlieb J.F.
Grof P.
Haarman B.C.M.
Harima H.
Hasse-Sousa M.
Henry C.
Hoffding L.
Houenou J.
Imbesi M.
Isometsä E.T.
Ivkovic M.
Janno S.
Johnsen S.
Kapczinski F.
Karakatsoulis G.N.
Kardell M.
Kessing L.V.
Kim S.J.
König B.
Kot T.L.
Koval M.
Kunz M.
Lafer B.
Landén M.
Larsen E.R.
Licht R.W.
Ludwig V.M.
Lopez-Jaramillo C.
MacKenzie A.
Madsen H.Ø.
Madsen S.A.K.A.
Mahadevan J.
Mahardika A.
Mahfoudh K.
Manchia M.
Marsh W.
Martinez-Cengotitabengoa M.
Martini J.
Martiny K.
Mashima Y.
McLoughlin D.M.
Meesters A.N.R.
Meesters Y.
Melle I.
Meza-Urzúa F.
Michaelis E.
Mikolas P.
Mok Y.M.
Monteith S.
Author's Affiliation
University of Toronto
Universidade de São Paulo
University of Melbourne
Université Paris-Saclay
Université Paris Cité
Karolinska Institutet
Michigan State University
Mayo Clinic
Helsingin Yliopisto
University of Glasgow
University of Ottawa
Northwestern University Feinberg School of Medicine
University of Münster
Universidade Federal do Rio Grande do Sul
Ben-Gurion University of the Negev
Universitair Medisch Centrum Groningen
Deakin University
Syddansk Universitet
Aalborg University
Hacettepe Üniversitesi
University of Massachusetts Chan Medical School
Università degli Studi di Cagliari
School of Medicine
Tartu Ülikool
Oslo Universitetssykehus
Copenhagen University Hospital
Sahlgrenska Akademin
Medizinische Universität Graz
Poznan University of Medical Sciences
Keio University School of Medicine
Universitätsklinikum Frankfurt
Universidad de Antioquia
Hôpital Bichat-Claude-Bernard AP-HP
Università Vita-Salute San Raffaele
Terveyden ja Hyvinvoinnin Laitos
Universitätsklinikum Carl Gustav Carus Dresden
IRCCS Ospedale San Raffaele
MSU College of Human Medicine
Dalhousie University, Faculty of Medicine
Chosun University
Başkent Üniversitesi
Aalborg Universitetshospital
Veterans General Hospital-Taichung Taiwan
National Institute of Mental Health and Neuro Sciences
University of Otago, Christchurch
Jane & Terry Semel Institute for Neuroscience & Human Behavior
Klinicki Centar Srbije
Bahir Dar University
Medizinische Fakultät
Department of Psychiatry
Institut Mondor de Recherche Biomédicale
International University of La Rioja
Instituto Nacional de Psiquiatría Ramon de la Fuente
Hospital Universitario Araba
Faculty of Health Sciences
Western Michigan University Homer Stryker M.D. School of Medicine
Azienda Ospedaliero Universitaria di Cagliari
University of Mataram
Singapore Institute of Mental Health
Dipartimento di Scienze Mediche, Chirurgiche e Neuroscienze
Selçuk Tip Fakültesi
University of Southern Denmark, Esbjerg
İstanbul Atlas Üniversitesi
Université de Tunis El Manar, Hôpital Razi
Tokyo Metropolitan Matsuzawa Hospital
St. Patrick's Hospital
Psychiatric Center Copenhagen
Instituto Psiquiatrico Dr. Jose Horwitz Barak
Centre ChronoS
ChronoRecord Association
Pine Rest Christian Mental Health Services
Butabika Hospital
BIPOLAR Zentrum Wiener Neustadt
Khanty-Mansiysk Clinical Psychoneurological Hospital
SHG-Klinik
Private Practice
Universidade de São Paulo
University of Melbourne
Université Paris-Saclay
Université Paris Cité
Karolinska Institutet
Michigan State University
Mayo Clinic
Helsingin Yliopisto
University of Glasgow
University of Ottawa
Northwestern University Feinberg School of Medicine
University of Münster
Universidade Federal do Rio Grande do Sul
Ben-Gurion University of the Negev
Universitair Medisch Centrum Groningen
Deakin University
Syddansk Universitet
Aalborg University
Hacettepe Üniversitesi
University of Massachusetts Chan Medical School
Università degli Studi di Cagliari
School of Medicine
Tartu Ülikool
Oslo Universitetssykehus
Copenhagen University Hospital
Sahlgrenska Akademin
Medizinische Universität Graz
Poznan University of Medical Sciences
Keio University School of Medicine
Universitätsklinikum Frankfurt
Universidad de Antioquia
Hôpital Bichat-Claude-Bernard AP-HP
Università Vita-Salute San Raffaele
Terveyden ja Hyvinvoinnin Laitos
Universitätsklinikum Carl Gustav Carus Dresden
IRCCS Ospedale San Raffaele
MSU College of Human Medicine
Dalhousie University, Faculty of Medicine
Chosun University
Başkent Üniversitesi
Aalborg Universitetshospital
Veterans General Hospital-Taichung Taiwan
National Institute of Mental Health and Neuro Sciences
University of Otago, Christchurch
Jane & Terry Semel Institute for Neuroscience & Human Behavior
Klinicki Centar Srbije
Bahir Dar University
Medizinische Fakultät
Department of Psychiatry
Institut Mondor de Recherche Biomédicale
International University of La Rioja
Instituto Nacional de Psiquiatría Ramon de la Fuente
Hospital Universitario Araba
Faculty of Health Sciences
Western Michigan University Homer Stryker M.D. School of Medicine
Azienda Ospedaliero Universitaria di Cagliari
University of Mataram
Singapore Institute of Mental Health
Dipartimento di Scienze Mediche, Chirurgiche e Neuroscienze
Selçuk Tip Fakültesi
University of Southern Denmark, Esbjerg
İstanbul Atlas Üniversitesi
Université de Tunis El Manar, Hôpital Razi
Tokyo Metropolitan Matsuzawa Hospital
St. Patrick's Hospital
Psychiatric Center Copenhagen
Instituto Psiquiatrico Dr. Jose Horwitz Barak
Centre ChronoS
ChronoRecord Association
Pine Rest Christian Mental Health Services
Butabika Hospital
BIPOLAR Zentrum Wiener Neustadt
Khanty-Mansiysk Clinical Psychoneurological Hospital
SHG-Klinik
Private Practice
Corresponding Author(s)
Other Contributor(s)
Abstract
Background: Sunlight has profound impacts on physical and mental health, beyond vision, including effects on circadian rhythms, alertness, mood, and sleep. A family history of any mood disorders is strongly associated with psychiatric disorders including bipolar disorder. The purpose of this study was to evaluate the association between a family history of any mood disorder in patients with bipolar I disorder and solar insolation at varied international onset locations. Methods: Data for this analysis were available from 5842 patients with a diagnosis of bipolar I disorder obtained at 83 collection sites in both hemispheres. This included 4752 patients from 71 collection sites in the northern hemisphere and 1090 patients from 12 collection sites in the southern hemisphere. Patient data variables were obtained from records or interviews. Solar insolation data were obtained from The National Aeronautics and Space Administration (NASA) Power database for each onset location, and the ratio of the mean monthly minimum/mean monthly maximum solar insolation was calculated. Typically, the ratio is largest near the equator (little yearly change in solar insolation) and smallest near the poles (large yearly change in solar insolation). Results: A significant relationship was found between a family history of any mood disorder, the ratio of the mean monthly minimum/mean monthly maximum solar insolation, and gender. The odds of a family history of mood disorder increased as patient location nears the poles and decreased near the equator. Female gender also increased the odds of having a family history of a mood disorder. Conclusions: This study highlighted the association between family history, solar insolation, and gender in international patients with bipolar I disorder. Given the profound effects of sunlight on human health, the family of patients with bipolar disorder who live in the same location with the same solar insolation, and especially females, may be at increased risk for a mood disorder.