Suicidality is most centrally situated within network of depression symptom criteria in unipolar depression patients with mood stabilizer in Asia
Issued Date
2024-11-01
Resource Type
ISSN
18762018
eISSN
18762026
Scopus ID
2-s2.0-85203273276
Journal Title
Asian Journal of Psychiatry
Volume
101
Rights Holder(s)
SCOPUS
Bibliographic Citation
Asian Journal of Psychiatry Vol.101 (2024)
Suggested Citation
Yoon J.W., Kim E., Jeong N., Kang M., Kim H.S., Lee S., Yoon H.J., Kim S.G., Na E., Yang H., Park J.H., Yang S.Y., Lin S.K., Zhu X., Xiang Y.T., Sim K., Tan C.H., Grover S., Avasthi A., Kallivayalil R.A., Maramis M.M., Chee K.Y., Pariwatcharakul P., Oo T., Kato T.A., Javed A., Chong M.Y., Sartorius N., Shinfuku N., Park J., Park S.C. Suicidality is most centrally situated within network of depression symptom criteria in unipolar depression patients with mood stabilizer in Asia. Asian Journal of Psychiatry Vol.101 (2024). doi:10.1016/j.ajp.2024.104197 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/101187
Title
Suicidality is most centrally situated within network of depression symptom criteria in unipolar depression patients with mood stabilizer in Asia
Author(s)
Yoon J.W.
Kim E.
Jeong N.
Kang M.
Kim H.S.
Lee S.
Yoon H.J.
Kim S.G.
Na E.
Yang H.
Park J.H.
Yang S.Y.
Lin S.K.
Zhu X.
Xiang Y.T.
Sim K.
Tan C.H.
Grover S.
Avasthi A.
Kallivayalil R.A.
Maramis M.M.
Chee K.Y.
Pariwatcharakul P.
Oo T.
Kato T.A.
Javed A.
Chong M.Y.
Sartorius N.
Shinfuku N.
Park J.
Park S.C.
Kim E.
Jeong N.
Kang M.
Kim H.S.
Lee S.
Yoon H.J.
Kim S.G.
Na E.
Yang H.
Park J.H.
Yang S.Y.
Lin S.K.
Zhu X.
Xiang Y.T.
Sim K.
Tan C.H.
Grover S.
Avasthi A.
Kallivayalil R.A.
Maramis M.M.
Chee K.Y.
Pariwatcharakul P.
Oo T.
Kato T.A.
Javed A.
Chong M.Y.
Sartorius N.
Shinfuku N.
Park J.
Park S.C.
Author's Affiliation
Hanyang University Hospital
Faculty of Health Sciences
Siriraj Hospital
Graduate School of Medical Sciences
The Affiliated Guangji Hospital of Soochow University
Jeju National University Hospital
Hanyang University Guri Hospital
University of Yangon
Universitas Airlangga
Chang Gung Memorial Hospital
Hanyang University College of Medicine
Taipei City Hospital Taiwan
Kuala Lumpur Hospital
Hanyang University
Seinan Gakuin University
University of Birmingham
National University of Singapore
Chosun University
Singapore Institute of Mental Health
Ajou University
Postgraduate Institute of Medical Education & Research, Chandigarh
Health Management International
Pushpagiri Institute of Medical Sciences
Yong-In Mental Hospital
Presbyterian Medical Center
Association for the Improvement of Mental Health Programs
Pakistan Psychiatric Research Centre
Regency Specialist Hospital
Faculty of Health Sciences
Siriraj Hospital
Graduate School of Medical Sciences
The Affiliated Guangji Hospital of Soochow University
Jeju National University Hospital
Hanyang University Guri Hospital
University of Yangon
Universitas Airlangga
Chang Gung Memorial Hospital
Hanyang University College of Medicine
Taipei City Hospital Taiwan
Kuala Lumpur Hospital
Hanyang University
Seinan Gakuin University
University of Birmingham
National University of Singapore
Chosun University
Singapore Institute of Mental Health
Ajou University
Postgraduate Institute of Medical Education & Research, Chandigarh
Health Management International
Pushpagiri Institute of Medical Sciences
Yong-In Mental Hospital
Presbyterian Medical Center
Association for the Improvement of Mental Health Programs
Pakistan Psychiatric Research Centre
Regency Specialist Hospital
Corresponding Author(s)
Other Contributor(s)
Abstract
Lithium and mood stabilizers are considered effective augmentation agents of antidepressants for treatment-resistant depression. Thus, this study aimed to estimate the network structure of depression symptom criteria among unipolar depression patients with mood stabilizers, using data from the Research on Asian Psychotropic Prescription Patterns for mood stabilizers (REAP-MS). We estimated a network of the 9 depression symptom criteria among 411 unipolar depression patients in Asia. Each of the depression symptom criteria was considered to be a dichotomous categorical variable. Suicidality (suicidal ideation or attempt) was the most centrally situated within the network of depression symptoms, followed by depressed mood, loss of energy, anhedonia and weight loss or gain. Contrastingly, concentration problem was the least interconnected. The depression symptom criteria were organized into 4 clusters by the community detection method. The findings suggest that suicidality may be one of the significant therapeutic target symptoms in unipolar depression patients with mood stabilizers.