Dual-function sensors based on carbon dots derived from corncobs for methyl nicotinate detection in solution and vapor phases
Issued Date
2022-12-01
Resource Type
ISSN
11440546
eISSN
13699261
Scopus ID
2-s2.0-85144685557
Journal Title
New Journal of Chemistry
Volume
47
Issue
3
Start Page
1129
End Page
1141
Rights Holder(s)
SCOPUS
Bibliographic Citation
New Journal of Chemistry Vol.47 No.3 (2022) , 1129-1141
Suggested Citation
Supchocksoonthorn P., Sinoy M.C.A., Kladsomboon S., de Luna M.D.G., Liang X., Song S., Paoprasert P. Dual-function sensors based on carbon dots derived from corncobs for methyl nicotinate detection in solution and vapor phases. New Journal of Chemistry Vol.47 No.3 (2022) , 1129-1141. 1141. doi:10.1039/d2nj05246f Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/84027
Title
Dual-function sensors based on carbon dots derived from corncobs for methyl nicotinate detection in solution and vapor phases
Other Contributor(s)
Abstract
Tuberculosis (TB) is a deadly disease and needs a fast, cheap, and effective method of detection at an early stage. Methyl nicotinate (MN) is an important TB biomarker, but there are only a few reports on MN sensing. In this study, fluorescence-based sensors and optical electronic nose sensors from carbon dots (CDs) were developed for the highly sensitive and selective detection of MN. They were able to detect MN in the solution phase via the inner filter effect (IFE) and strong π-π interactions between the pyridine ring and the CDs. The limit of detection was found to be dependent upon the excitation wavelength and concentration of CDs. The use of 0.05 mg mL−1 CDs and 260 nm excitation provided the best linearity range of over 5-500 μM and the lowest detection limit of 3 nM. The CDs showed excellent photostability and good selectivity towards MN in the presence of several interferences. This work demonstrated the practical use of the CDs when tested in MN spiked biological samples, with 98.8-102.9% recovery percentage. The fabrication of reusable paper-based sensors was also demonstrated. The CD thin film integrated in the optical electronic nose could sense MN vapor and distinguish MN from other biomarkers. The CDs developed in this work can be potentially used as dual-mode sensors for early TB detection.