Red light emitting diode as an adjuvant treatment for epidermal growth factor receptor inhibitors-induced paronychia
Issued Date
2022-01-01
Resource Type
ISSN
09546634
eISSN
14711753
Scopus ID
2-s2.0-85106251194
Pubmed ID
33961534
Journal Title
Journal of Dermatological Treatment
Volume
33
Issue
4
Start Page
1990
End Page
1994
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Dermatological Treatment Vol.33 No.4 (2022) , 1990-1994
Suggested Citation
Jornsamer C. Red light emitting diode as an adjuvant treatment for epidermal growth factor receptor inhibitors-induced paronychia. Journal of Dermatological Treatment Vol.33 No.4 (2022) , 1990-1994. 1994. doi:10.1080/09546634.2021.1927950 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/86771
Title
Red light emitting diode as an adjuvant treatment for epidermal growth factor receptor inhibitors-induced paronychia
Author(s)
Author's Affiliation
Other Contributor(s)
Abstract
We evaluated the efficacy and safety of red light LED as an adjuvant treatment for epidermal growth factor receptor inhibitor-induced paronychia. Eight patients were recruited in this randomized, single-blinded controlled trial. They were randomized to receive red-light on one hand or foot 2–3 times/week for 6 weeks while the contralateral side served as controls. The standard treatments were continued. Erythema and lesion elevation observed by Anthera® 3D, severity and pain scores were obtained at weeks 0, 2, 4, 6, and 8. The red light group showed significantly lower erythema, severity, and pain scores at weeks 4, 6, and 8. The elevation was significantly lower in the red light group at every follow-up visit. No adverse events occurred. Red light therapy may be an option as adjunctive treatment for EGFRi-induced paronychia.
