Talaromyces marneffei Infection: Virulence, Intracellular Lifestyle and Host Defense Mechanisms
Issued Date
2022-02-01
Resource Type
eISSN
2309608X
Scopus ID
2-s2.0-85125036606
Journal Title
Journal of Fungi
Volume
8
Issue
2
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Fungi Vol.8 No.2 (2022)
Suggested Citation
Pruksaphon K., Nosanchuk J.D., Ratanabanangkoon K., Youngchim S. Talaromyces marneffei Infection: Virulence, Intracellular Lifestyle and Host Defense Mechanisms. Journal of Fungi Vol.8 No.2 (2022). doi:10.3390/jof8020200 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/86143
Title
Talaromyces marneffei Infection: Virulence, Intracellular Lifestyle and Host Defense Mechanisms
Other Contributor(s)
Abstract
Talaromycosis (Penicilliosis) is an opportunistic mycosis caused by the thermally dimor-phic fungus Talaromyces (Penicillium) marneffei. Similar to other major causes of systemic mycoses, the extent of disease and outcomes are the results of complex interactions between this opportunistic human pathogen and a host’s immune response. This review will highlight the current knowledge regarding the dynamic interaction between T. marneffei and mammalian hosts, particularly highlighting important aspects of virulence factors, intracellular lifestyle and the mechanisms of immune defense as well as the strategies of the pathogen for manipulating and evading host immune cells.