The Biosafety Research Road Map: The Search for Evidence to Support Practices in the Laboratory—Foot and Mouth Disease Virus
Issued Date
2023-01-01
Resource Type
ISSN
15356760
eISSN
24701246
Scopus ID
2-s2.0-85167888328
Journal Title
Applied Biosafety
Rights Holder(s)
SCOPUS
Bibliographic Citation
Applied Biosafety (2023)
Suggested Citation
Blacksell S.D., Dhawan S., Kusumoto M., Le K.K., Summermatter K., O'Keefe J., Kozlovac J., Almuhairi S.S., Sendow I., Scheel C.M., Ahumibe A., Masuku Z.M., Bennett A.M., Kojima K., Harper D.R., Hamilton K. The Biosafety Research Road Map: The Search for Evidence to Support Practices in the Laboratory—Foot and Mouth Disease Virus. Applied Biosafety (2023). doi:10.1089/apb.2022.0041 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/88832
Title
The Biosafety Research Road Map: The Search for Evidence to Support Practices in the Laboratory—Foot and Mouth Disease Virus
Author's Affiliation
World Organisation for Animal Health (WOAH)
UK Health Security Agency
Mahidol Oxford Tropical Medicine Research Unit
Nigeria Centre for Disease Control
National Institute for Communicable Diseases
Organisation Mondiale de la Santé
Centers for Disease Control and Prevention
Chatham House
University of Bern
Nuffield Department of Medicine
USDA ARS Beltsville Agricultural Research Center
Abu Dhabi Agriculture and Food Safety Authority
Ministry for Primary Industries
Indonesian Research Center for Veterinary Science
UK Health Security Agency
Mahidol Oxford Tropical Medicine Research Unit
Nigeria Centre for Disease Control
National Institute for Communicable Diseases
Organisation Mondiale de la Santé
Centers for Disease Control and Prevention
Chatham House
University of Bern
Nuffield Department of Medicine
USDA ARS Beltsville Agricultural Research Center
Abu Dhabi Agriculture and Food Safety Authority
Ministry for Primary Industries
Indonesian Research Center for Veterinary Science
Other Contributor(s)
Abstract
Introduction: Foot and mouth disease (FMD) is a highly contagious infection of cloven-hoofed animals. The Biosafety Research Road Map reviewed scientific literature regarding the foot and mouth disease virus (FMDV). This project aims to identify gaps in the data required to conduct evidence-based biorisk assessments, as described by Blacksell et al., and strengthen control measures appropriate for local and national laboratories. Methods: A literature search was conducted to identify potential gaps in biosafety and focused on five main sections: the route of inoculation/modes of transmission, infectious dose, laboratory-acquired infections, containment releases, and disinfection and decontamination strategies. Results: The available data regarding biosafety knowledge gaps and existing evidence have been collated. Some gaps include the need for more scientific data that identify the specific safety contribution of engineering controls, support requirements for showering out after in vitro laboratory work, and whether a 3- to 5-day quarantine period should be applied to individuals conducting in vitro versus in vivo work. Addressing these gaps will contribute to the remediation and improvement of biosafety and biosecurity systems when working with FMDV.