China’s Malaria R&D Innovations: A Scoping Review from 2013–2023
Issued Date
2025-05-02
Resource Type
ISSN
20967071
Scopus ID
2-s2.0-105005278520
Journal Title
China CDC Weekly
Volume
7
Issue
18
Start Page
635
End Page
643
Rights Holder(s)
SCOPUS
Bibliographic Citation
China CDC Weekly Vol.7 No.18 (2025) , 635-643
Suggested Citation
Wang S., Ding W., Lu S., Li L., Qian F., Chen C., Liu L., Cai Y., Liu X., Perez S., Frutos R., Yao H., Zhou Y., Ye C., Wu D., Li S., Jiang Kwete X., Sui Y., Wang D. China’s Malaria R&D Innovations: A Scoping Review from 2013–2023. China CDC Weekly Vol.7 No.18 (2025) , 635-643. 643. doi:10.46234/ccdcw2025.105 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/110334
Title
China’s Malaria R&D Innovations: A Scoping Review from 2013–2023
Author's Affiliation
Fred Hutchinson Cancer Center
Interactions Hôtes-Vecteurs-Parasites-Environnement Dans les Maladies Tropicales Négligées dues aux Trypanosomatides (INTERTRYP)
Étude des Structures et des Processus d’Adaptation et des Changements de l’Espace
Shanghai University of Medicine & Health Sciences
Shanghai Jiao Tong University School of Medicine
Universitas Airlangga
Chinese Center for Disease Control and Prevention
Faculty of Medicine Ramathibodi Hospital, Mahidol University
The University of Hong Kong
Zhejiang University
Ltd
Global Health Research and Consulting
Interactions Hôtes-Vecteurs-Parasites-Environnement Dans les Maladies Tropicales Négligées dues aux Trypanosomatides (INTERTRYP)
Étude des Structures et des Processus d’Adaptation et des Changements de l’Espace
Shanghai University of Medicine & Health Sciences
Shanghai Jiao Tong University School of Medicine
Universitas Airlangga
Chinese Center for Disease Control and Prevention
Faculty of Medicine Ramathibodi Hospital, Mahidol University
The University of Hong Kong
Zhejiang University
Ltd
Global Health Research and Consulting
Corresponding Author(s)
Other Contributor(s)
Abstract
Malaria remains a major global health challenge. Understanding the research progress of the potential innovative tools is important for malaria elimination. This scoping review aims to explore China’s research and development (R&D) advances from 2013–2023 in addressing the current challenges and contributing to global malaria elimination. Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR), this review searched the English and Simplified Chinese data sources from five databases. A total of 11,112 English articles and 2,944 Chinese articles were retrieved. After screening, 44 English and 13 Chinese articles were included. Key advancements were identified in three domains: vector control, pathogen screening and diagnosis, and prevention and treatment. Innovations in vector control include studies such as the use of Serratia strains and symbiont-mediated RNAi approaches to block malaria transmission. Advances in pathogen screening and diagnosis feature biosensor development, AI monitoring technologies, and novel amplification gene and nucleic acid detection technologies. In prevention and treatment, artemisinin-based combination therapies (ACTs) remain a cornerstone, with additional progress in industrial pharmaceuticals and technologies already in field and semi-field-testing stages. This review underscores the importance of leveraging China’s R&D capacity to meet global challenges. To maximize impact, we call for global attention to strengthening international collaboration with China in malaria R&D to accelerate the commercialization, regulatory approval, and large-scale deployment of innovations.