Targeting quorum sensing and biofilm formation in the control of Vibrio harveyi infections in Penaeus vannamei
Issued Date
2022-10-01
Resource Type
ISSN
1355557X
eISSN
13652109
Scopus ID
2-s2.0-85133598160
Journal Title
Aquaculture Research
Volume
53
Issue
14
Start Page
4919
End Page
4930
Rights Holder(s)
SCOPUS
Bibliographic Citation
Aquaculture Research Vol.53 No.14 (2022) , 4919-4930
Suggested Citation
Guzman J.P.M.D., Yatip P., Soowannayan C., Maningas M.B.B. Targeting quorum sensing and biofilm formation in the control of Vibrio harveyi infections in Penaeus vannamei. Aquaculture Research Vol.53 No.14 (2022) , 4919-4930. 4930. doi:10.1111/are.15995 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/83134
Title
Targeting quorum sensing and biofilm formation in the control of Vibrio harveyi infections in Penaeus vannamei
Author(s)
Other Contributor(s)
Abstract
Vibriosis, a disease caused by Vibrio spp., including V. harveyi, contributes to enormous economic loss to the shrimp aquaculture industry. With the worsening incidences of antimicrobial resistance in aquaculture, novel strategies for combating this bacterial infection are urgently needed. One of these is by targeting the bacterial communication system, called quorum sensing (QS), which is responsible for the expression of genes necessary for bacterial pathogenesis. Recently, bioactive compounds capable of inhibiting QS were identified. This review focuses on the discovery of bioactive substances from animal, plant, and microbial origins with the capability of inhibiting QS and biofilm formation, a mechanism important in the pathogenesis of vibriosis. Furthermore, recent developments in the use of these QS inhibitors (QSIs) as feed supplement for Penaeus vannamei shrimp were also discussed. These findings will provide the necessary information for the discovery, development, and eventual commercialization of these QSIs as tools in mitigating vibriosis in the shrimp industry.