Feature-Based Classification of Mild Cognitive Impairment and Alzheimer’s Disease Based on Optical Coherence Tomographic Angiographic Image
Issued Date
2024-08-01
Resource Type
eISSN
14248220
Scopus ID
2-s2.0-85202443420
Journal Title
Sensors
Volume
24
Issue
16
Rights Holder(s)
SCOPUS
Bibliographic Citation
Sensors Vol.24 No.16 (2024)
Suggested Citation
Visitsattapongse S., Maneerat A., Trinavarat A., Rattanabannakit C., Morkphrom E., Senanarong V., Srinonprasert V., Songsaeng D., Atchaneeyasakul L.O., Pintavirooj C. Feature-Based Classification of Mild Cognitive Impairment and Alzheimer’s Disease Based on Optical Coherence Tomographic Angiographic Image. Sensors Vol.24 No.16 (2024). doi:10.3390/s24165192 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/100929
Title
Feature-Based Classification of Mild Cognitive Impairment and Alzheimer’s Disease Based on Optical Coherence Tomographic Angiographic Image
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Abstract
Alzheimer’s disease is a type of neurodegenerative disorder that is characterized by the progressive degeneration of brain cells, leading to cognitive decline and memory loss. It is the most common cause of dementia and affects millions of people worldwide. While there is currently no cure for Alzheimer’s disease, early detection and treatment can help to slow the progression of symptoms and improve quality of life. This research presents a diagnostic tool for classifying mild cognitive impairment and Alzheimer’s diseases using feature-based machine learning applied to optical coherence tomographic angiography images (OCT-A). Several features are extracted from the OCT-A image, including vessel density in five sectors, the area of the foveal avascular zone, retinal thickness, and novel features based on the histogram of the range-filtered OCT-A image. To ensure effectiveness for a diverse population, a large local database for our study was collected. The promising results of our study, with the best accuracy of 92.17,% will provide an efficient diagnostic tool for early detection of Alzheimer’s disease.