A novel technique in reducing sebum production and improving atrophic acne scars

dc.contributor.authorSirithanabadeekul P.
dc.contributor.authorLeetrakulwanna V.
dc.contributor.authorSuwanchinda A.
dc.contributor.otherMahidol University
dc.date.accessioned2023-06-18T17:41:43Z
dc.date.available2023-06-18T17:41:43Z
dc.date.issued2022-11-01
dc.description.abstractObjective: Fractional microneedling radiofrequency (FMR) has gained popularity for the treatment of acne scars, owing to favorable outcomes and short downtimes. This study aimed to investigate FMR use in reducing facial sebum production and treating acne scars. Materials and Methods: This single-center, prospective, evaluator-blinded trial compared sebum production after three sessions of FMR (Fractora® 24-pin coated tip) performed one-month apart. Results were evaluated with a sebumeter (Cutometer®), sebaceous gland histology, and subjects' assessment. Acne scars were graded according to the Echelle d'Evaluation clinique des Cicatrices d'acné scale, Goodman and Baron's qualitative grading system, acne scar volume measurement, and subjects' assessments. Results: Sebumeter results revealed a significantly decreased (p < 0.05) sebum production since the first treatment, sustained throughout the study period. Histological assessment showed decreased density and size of sebaceous glands. The mean acne scar volume decreased significantly, without a significant increase in the mean melanin levels. Conclusion: Fractora® 24-pin coated tip can be used as an alternative for patients with acne scars, who wish to concomitantly reduce their facial oiliness. A significant decrease in facial oiliness and acne scars' volume can be seen after a single treatment session, with up to 15.48% decrease in facial oil production.
dc.identifier.citationJournal of Cosmetic Dermatology Vol.21 No.11 (2022) , 5872-5879
dc.identifier.doi10.1111/jocd.15137
dc.identifier.eissn14732165
dc.identifier.issn14732130
dc.identifier.pmid35642576
dc.identifier.scopus2-s2.0-85132333908
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/85439
dc.rights.holderSCOPUS
dc.subjectMedicine
dc.titleA novel technique in reducing sebum production and improving atrophic acne scars
dc.typeArticle
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85132333908&origin=inward
oaire.citation.endPage5879
oaire.citation.issue11
oaire.citation.startPage5872
oaire.citation.titleJournal of Cosmetic Dermatology
oaire.citation.volume21
oairecerif.author.affiliationRamathibodi Hospital
oairecerif.author.affiliationThammasat University

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