Alteration of gut microbiota in wild-borne long-tailed macaques after 1-year being housed in hygienic captivity
1
Issued Date
2023-12-01
Resource Type
eISSN
20452322
Scopus ID
2-s2.0-85152111098
Pubmed ID
37037869
Journal Title
Scientific Reports
Volume
13
Issue
1
Rights Holder(s)
SCOPUS
Bibliographic Citation
Scientific Reports Vol.13 No.1 (2023)
Suggested Citation
Sawaswong V., Chanchaem P., Kemthong T., Warit S., Chaiprasert A., Malaivijitnond S., Payungporn S. Alteration of gut microbiota in wild-borne long-tailed macaques after 1-year being housed in hygienic captivity. Scientific Reports Vol.13 No.1 (2023). doi:10.1038/s41598-023-33163-6 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/82107
Title
Alteration of gut microbiota in wild-borne long-tailed macaques after 1-year being housed in hygienic captivity
Other Contributor(s)
Abstract
The wild-born long-tailed macaques (Macaca fascicularis) were recently recruited and used as breeders for the National Primate Research Center of Thailand, Chulalongkorn University (NPRCT-CU), and changes in their in-depth gut microbiota profiles were investigated. The Oxford Nanopore Technology (ONT) was used to explore full-length 16S rDNA sequences of gut microbiota in animals once captured in their natural habitat and 1-year following translocation and housing in a hygienic environment at NPRCT-CU. Our findings show that the gut microbiota of macaques after 1 year of hygienic housing and programmed diets feeding was altered and reshaped. The prevalent gut bacteria such as Prevotella copri and Faecalibacterium prausnitzii were enriched after translocation, causing the lower alpha diversity. The correlation analysis revealed that Prevotella copri, Phascolarctobacterium succinatutens, and Prevotella stercorea, showed a positive correlation with each other. Significantly enriched pathways in the macaques after translocation included biosynthesis of essential amino acids, fatty acids, polyamine and butanoate. The effects of microbiota change could help macaques to harvest the energy from programmed diets and adapt their gut metabolism. The novel probiotics and microbiota engineering approach could be further developed based on the current findings and should be helpful for captive animal health care management.