Frailty and intrinsic capacity: integrating complementary concepts to promote healthy ageing and transformation of care

dc.contributor.authorCesari M.
dc.contributor.authorCanevelli M.
dc.contributor.authorAmuthavalli Thiyagarajan J.
dc.contributor.authorArai H.
dc.contributor.authorAssantachai P.
dc.contributor.authorChan P.
dc.contributor.authorChhetri J.K.
dc.contributor.authorFerriolli E.
dc.contributor.authorGeffen L.
dc.contributor.authorGregson C.L.
dc.contributor.authorGuaraldi G.
dc.contributor.authorGutierrez Robledo L.M.
dc.contributor.authorHammami S.
dc.contributor.authorJang H.
dc.contributor.authorKalula S.
dc.contributor.authorMathur A.
dc.contributor.authorMerchant R.A.
dc.contributor.authorOliveira D.
dc.contributor.authorPerracini M.R.
dc.contributor.authorPetrovic M.
dc.contributor.authorPolidori-Nelles M.C.
dc.contributor.authorRodriguez Mañas L.
dc.contributor.authorRowe J.W.
dc.contributor.authorSabzwari S.
dc.contributor.authorSadana R.
dc.contributor.authorSumi Y.
dc.contributor.authorTomarevska O.
dc.contributor.authorVellas B.
dc.contributor.authorVisvanathan R.
dc.contributor.authorWoo J.
dc.contributor.authorMartin F.C.
dc.contributor.correspondenceCesari M.
dc.contributor.otherMahidol University
dc.date.accessioned2026-05-28T18:39:52Z
dc.date.available2026-05-28T18:39:52Z
dc.date.issued2026-05-01
dc.description.abstractAs the global population ages, especially in low- and middle-income countries, there is an urgent need to rethink how health in older age is understood and addressed. Frailty has long served as a clinical construct to identify vulnerability and guide tailored, specialist care for older people. In 2015, the World Health Organisation introduced the concept of intrinsic capacity (IC) as part of its healthy ageing framework, offering a structured, capacity-based approach to promote functional ability. While conceptually distinct, frailty and IC are complementary. Frailty highlights the need for specialised care in complex cases, whereas IC supports early intervention and prevention across broader populations. This paper explores their differences, areas of overlap and how their integration can support a continuum of care that spans primary to specialist settings. Integrating these concepts connects prevention, health promotion and complex care management. By aligning clinical and public health perspectives, the combined use of frailty and IC offers a holistic, person-centred approach to care system transformation, with the potential to drive coordinated strategies that strengthen both geriatric practice and public health across diverse populations.
dc.identifier.citationAge and Ageing Vol.55 No.5 (2026)
dc.identifier.doi10.1093/ageing/afag138
dc.identifier.eissn14682834
dc.identifier.issn00020729
dc.identifier.scopus2-s2.0-105039438139
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/123456789/116962
dc.rights.holderSCOPUS
dc.subjectBiochemistry, Genetics and Molecular Biology
dc.subjectMedicine
dc.titleFrailty and intrinsic capacity: integrating complementary concepts to promote healthy ageing and transformation of care
dc.typeArticle
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=105039438139&origin=inward
oaire.citation.issue5
oaire.citation.titleAge and Ageing
oaire.citation.volume55
oairecerif.author.affiliationUniversidade de São Paulo
oairecerif.author.affiliationSapienza Università di Roma
oairecerif.author.affiliationUniversiteit Gent
oairecerif.author.affiliationUniversity of Bristol
oairecerif.author.affiliationUniversität zu Köln
oairecerif.author.affiliationUniversity of Cape Town
oairecerif.author.affiliationUniversità degli Studi di Modena e Reggio Emilia
oairecerif.author.affiliationFaculty of Life Sciences & Medicine
oairecerif.author.affiliationOrganisation Mondiale de la Santé
oairecerif.author.affiliationUniklinik Köln
oairecerif.author.affiliationMailman School of Public Health
oairecerif.author.affiliationThe Aga Khan University
oairecerif.author.affiliationCHU de Toulouse
oairecerif.author.affiliationSiriraj Hospital
oairecerif.author.affiliationUniversidad Andrés Bello
oairecerif.author.affiliationNational University Hospital
oairecerif.author.affiliationUniversité de Monastir
oairecerif.author.affiliationXuanwu Hospital, Capital Medical University
oairecerif.author.affiliationAdelaide Medical School
oairecerif.author.affiliationNational Center for Geriatrics and Gerontology
oairecerif.author.affiliationSA Health
oairecerif.author.affiliationCERPOP - Centre d'Epidémiologie et de Recherche en Santé des Populations
oairecerif.author.affiliationUniversidade Cidade de São Paulo
oairecerif.author.affiliationInstitute of Gerontology Academy of Medical Sciences of Ukraine
oairecerif.author.affiliationDr. Sampurnanand Medical College
oairecerif.author.affiliationInstituto Nacional de Geriatría
oairecerif.author.affiliationBiomedical Research and Training Institute Harare
oairecerif.author.affiliationInstituto Milenio para la Investigación del Cuidado
oairecerif.author.affiliationNepalese Society of Gerontology and Geriatrics
oairecerif.author.affiliationJockey Club Institute of Ageing
oairecerif.author.affiliationHospital Universitario de Getafe

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