Iliopsoas haemorrhage complicated by femoral neuropathy in patients with haemophilia: a case series report
1
Issued Date
2023-02-01
Resource Type
ISSN
09255710
eISSN
18653774
Scopus ID
2-s2.0-85138747268
Pubmed ID
36151351
Journal Title
International Journal of Hematology
Volume
117
Issue
2
Start Page
293
End Page
306
Rights Holder(s)
SCOPUS
Bibliographic Citation
International Journal of Hematology Vol.117 No.2 (2023) , 293-306
Suggested Citation
Panuwannakorn M., Jiravichitchai T., Lertthammakiat S., Jaovisidha S., Sirachainan N., Chuansumrit A. Iliopsoas haemorrhage complicated by femoral neuropathy in patients with haemophilia: a case series report. International Journal of Hematology Vol.117 No.2 (2023) , 293-306. 306. doi:10.1007/s12185-022-03456-z Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/82446
Title
Iliopsoas haemorrhage complicated by femoral neuropathy in patients with haemophilia: a case series report
Author's Affiliation
Other Contributor(s)
Abstract
Objectives: The study aimed to determine the incidence of femoral neuropathy in patients with haemophilia exhibiting iliopsoas haemorrhage. Methods: Patients with iliopsoas haemorrhage confirmed by ultrasonography or CT scan were studied retrospectively. Results: A total of 44 episodes of iliopsoas haemorrhage occurred in 20 patients with haemophilia (A17, B3). Most episodes in patients without inhibitors (14/16 = 87.5%) were adequately treated followed by prophylaxis. However, 11 of 28 episodes (39.3%) in patients with inhibitors were adequately treated and no prophylaxis was provided. An appropriate rehabilitation programme was arranged during hospitalisation and follow-up. Femoral neuropathy was observed in 28 of 44 episodes, while 16 episodes of persistent femoral neuropathy from previous bleeding were excluded. As a result, 11 of 28 episodes (39.3%) of femoral neuropathy were similarly found amongst patients with and without inhibitors. The mean time of onset and resolution of femoral neuropathy were 3.7 (1.8) and 23.4 (20.5) days after the onset of iliopsoas haemorrhage, respectively. Patients receiving inadequate and delayed replacement had a significantly higher rate of femoral neuropathy than those who received adequate and prompt replacement. Conclusion: Femoral neuropathy following iliopsoas haemorrhage was common in haemophilia patients with and without inhibitors.