Nerve Capping Using Renerve® Synthetic Collagen Conduits for Hand Amputation Neuroma Pain
Issued Date
2025-01-01
Resource Type
ISSN
24248355
eISSN
24248363
Scopus ID
2-s2.0-85214562768
Journal Title
Journal of Hand Surgery Asian-Pacific Volume
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Hand Surgery Asian-Pacific Volume (2025)
Suggested Citation
Takeda S., Kurimoto S., Shibata R., Mitsuya S., Okamoto H., Murakami H. Nerve Capping Using Renerve® Synthetic Collagen Conduits for Hand Amputation Neuroma Pain. Journal of Hand Surgery Asian-Pacific Volume (2025). doi:10.1142/S2424835525500195 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/102943
Title
Nerve Capping Using Renerve® Synthetic Collagen Conduits for Hand Amputation Neuroma Pain
Corresponding Author(s)
Other Contributor(s)
Abstract
Background: Amputated neuromas, a common consequence of peripheral nerve injury, can cause significant pain and may impair daily life. Herein, we conducted a retrospective study on patients who underwent a nerve-capping technique using the bioabsorbable nerve conduit Renerve®, with a minimum follow-up period of 6 months. Methods: We conducted a retrospective study to assess patients with amputation neuromas of the finger or palm who underwent surgical treatment using the capping technique with the Renerve® conduit between October 2018 and September 2022. The data on demographics, operative details, pre- and postoperative evaluations (visual analogue scale [VAS] pain scores and Tinel sign) and complications were analysed. Results: Seven patients (seven nerves) with a median age of 51 years (three men and four women) were assessed. The median follow-up duration was 15 months. Renerve® conduits of varying sizes (1.0-2.3 mm) and lengths (15-25 mm) were used. The median duration until surgery was 195 days. After the procedure, VAS pain scores significantly decreased from a baseline of 53.1 mm to 5.7 mm at the 6-month follow-up. Tinel sign persisted in four patients, and no postoperative complications occurred. Conclusions: Our study demonstrates the clinical usefulness of the Renerve® conduit as a nerve-capping technique for amputation neuroma. Considering the limited availability of real-world data on Renerve® conduits for nerve capping, our findings provide valuable insights for clinical practitioners.