Intestinal obstruction from calcium polystyrene sulfonate in pediatric cancer patients
20
Issued Date
2022-12-01
Resource Type
eISSN
24681245
Scopus ID
2-s2.0-85157234027
Journal Title
Pediatric Hematology Oncology Journal
Volume
7
Issue
4
Start Page
122
End Page
125
Rights Holder(s)
SCOPUS
Bibliographic Citation
Pediatric Hematology Oncology Journal Vol.7 No.4 (2022) , 122-125
Suggested Citation
Getsuwan S., Komwilaisak P., Laoaroon N., Tanming P., Suwannaying K., Wiangnon S., Jetsrisuparb A. Intestinal obstruction from calcium polystyrene sulfonate in pediatric cancer patients. Pediatric Hematology Oncology Journal Vol.7 No.4 (2022) , 122-125. 125. doi:10.1016/j.phoj.2022.07.001 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/87153
Title
Intestinal obstruction from calcium polystyrene sulfonate in pediatric cancer patients
Other Contributor(s)
Abstract
Tumor lysis syndrome (TLS) is common in some childhood hematologic malignancies. Calcium polystyrene sulfonate (CPS) is occasionally prescribed for hyperkalemia in TLS. We reported two children with intestinal obstruction, a serious adverse effect from high-dose CPS. Both cases were constipated prior to chemotherapy with vincristine. While one patient recovered from the obstruction by surgery, the other was successfully managed by manual evacuation. After the obstruction, both children experienced recurrent constipation, which was aggravated by vincristine. Using CPS in children with preexisting constipation or ileus could lead to adverse outcomes. We would like to propose that effective treatment for fecal disimpaction is necessary when starting CPS with vincristine in children with constipation.