Thyroid Incidentalomas in Hospitalized Patients With COVID-19: A Single-Center Retrospective Analysis
Issued Date
2023-06-01
Resource Type
eISSN
24721972
Scopus ID
2-s2.0-85165928256
Journal Title
Journal of the Endocrine Society
Volume
7
Issue
6
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of the Endocrine Society Vol.7 No.6 (2023)
Suggested Citation
Jantarapootirat M., Traiwanatham S., Hirunpat P., Boonsomsuk W., Sungkanuparph S., Sriphrapradang C. Thyroid Incidentalomas in Hospitalized Patients With COVID-19: A Single-Center Retrospective Analysis. Journal of the Endocrine Society Vol.7 No.6 (2023). doi:10.1210/jendso/bvad060 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/88239
Title
Thyroid Incidentalomas in Hospitalized Patients With COVID-19: A Single-Center Retrospective Analysis
Author's Affiliation
Other Contributor(s)
Abstract
Context: During the COVID-19 pandemic, both people with underlying diseases and previously healthy people were infected with SARS-CoV-2. In our institute, most hospitalized patients underwent chest computed tomography (CT) to evaluate pulmonary involvement and complication of COVID-19. There are currently limited data regarding thyroid CT incidentalomas in healthy people. Objective: We aimed to investigate the prevalence and predictors of thyroid incidentalomas among hospitalized patients with COVID-19. Methods: A single-center retrospective study included hospitalized patients aged ≥15 years with COVID-19 who underwent chest CT during April 2020 and October 2021. Thyroid incidentalomas were reviewed and identified by an experienced radiologist. Logistic regression analysis was used to determine predictors for thyroid incidentalomas. Results: In the 1326 patients (mean age 49.4 years and 55.3% female) that were included, the prevalence of thyroid incidentalomas was 20.2%. Patients with thyroid incidentalomas were older (59.6 years vs 46.8 years, P < .001) and more often female than those without incidentalomas (63.4% vs 53.2%, P = .003). On multivariate analysis, only female sex (OR 1.56; 95% CI 1.17-2.07) and older age (OR 1.04; 95% CI 1.03-1.05) were significantly associated with thyroid incidentalomas. Conclusion: In COVID-19 patients, the prevalence of thyroid incidentalomas identified on chest CT was higher (20.2%) than in previous studies in the general population (<1% to 16.8%). Female sex and older age were independent factors associated with thyroid incidentalomas.