Body Mass Index Combined With Possible Sarcopenia Status Is Better Than BMI or Possible Sarcopenia Status Alone for Predicting All-Cause Mortality Among Asian Community-Dwelling Older Adults
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Issued Date
2022-06-30
Resource Type
eISSN
2296861X
Scopus ID
2-s2.0-85134212346
Journal Title
Frontiers in Nutrition
Volume
9
Rights Holder(s)
SCOPUS
Bibliographic Citation
Frontiers in Nutrition Vol.9 (2022)
Suggested Citation
Chalermsri C., Aekplakorn W., Srinonprasert V. Body Mass Index Combined With Possible Sarcopenia Status Is Better Than BMI or Possible Sarcopenia Status Alone for Predicting All-Cause Mortality Among Asian Community-Dwelling Older Adults. Frontiers in Nutrition Vol.9 (2022). doi:10.3389/fnut.2022.881121 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/85789
Title
Body Mass Index Combined With Possible Sarcopenia Status Is Better Than BMI or Possible Sarcopenia Status Alone for Predicting All-Cause Mortality Among Asian Community-Dwelling Older Adults
Author(s)
Other Contributor(s)
Abstract
Background: Body mass index (BMI) and sarcopenia are common indicators of nutritional status. Possible sarcopenia, defined as low muscle strength or performance, was recently introduced by the Asian Working Group for Sarcopenia (AWGS) in 2019. We investigated for association between all-cause mortality and BMI combined with possible sarcopenia severity in Asian older adults. Methods: This study included a subpopulation (8,195 participants aged ≥60 years; male gender: 49.4%; mean age: 69.2 ± 6.8 years) from the Fourth Thai National Health Examination Survey (NHES-IV). BMI was classified using Asia-Pacific cut-offs. Possible sarcopenia was defined using quadriceps strength based on AWGS 2019 criteria, and possible sarcopenia severity was determined using study population quartile cut-offs. All-cause mortality data was derived from the national vital registry in 2020. Results: The prevalence of underweight status and possible sarcopenia was 11.8 and 38.9%, respectively. Multivariate analysis showed underweight individuals with severe possible sarcopenia to be at highest risk for increased mortality [adjusted hazard ratio (aHR): 3.98, 95% confidence interval (CI): 2.89–5.48], and higher risk was found in men compared to women (aHR: 5.35, 95% CI: 1.19–8.97). Obese status without possible sarcopenia was an independent protective factor (aHR: 0.61, 95% CI: 0.38–0.97). Conclusion: BMI combined with possible sarcopenia severity is a better predictor of mortality risk than either parameter alone.