Do different platforms of coronavirus vaccines have different impacts on psoriasis flares?
1
Issued Date
2023-01-01
Resource Type
ISSN
09066705
eISSN
16000625
Scopus ID
2-s2.0-85150894301
Pubmed ID
36940925
Journal Title
Experimental Dermatology
Rights Holder(s)
SCOPUS
Bibliographic Citation
Experimental Dermatology (2023)
Suggested Citation
Chularojanamontri L., Likittanasombat S., Chaiyabutr C., Silpa-archa N., Wongpraparut C. Do different platforms of coronavirus vaccines have different impacts on psoriasis flares?. Experimental Dermatology (2023). doi:10.1111/exd.14793 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/82322
Title
Do different platforms of coronavirus vaccines have different impacts on psoriasis flares?
Author's Affiliation
Other Contributor(s)
Abstract
This study evaluated the impacts on psoriasis flares of 3 vaccine platforms: inactivated, viral vector and mRNA. Respectively, 198 and 96 psoriasis patients with and without COVID-19 vaccination during the study period. Group comparison revealed no increased risk of psoriasis flaring after COVID-19 vaccination. The vaccinated group received 425 doses of vaccine (140 inactivated, 230 viral vector and 55 mRNA). Patients' self-reported symptoms included all three platforms causing psoriasis flare, but the highest was among patients administered with mRNA vaccines. Most flares were mild to moderate, and most patients (89.8%) managed their flare-up lesions without rescue therapy. In conclusion, our study showed that the rate of psoriasis flare was not significantly different between vaccinated and unvaccinated groups. Factors that might explain psoriasis flare include vaccine-related psychological stress and side effects from vaccination. Different platforms of corona vaccines seemed to have different impact of psoriasis flares. Based on our results and the recommendations of several consensus guidelines, the benefits of COVID vaccinations outweigh the risks to patients with psoriasis. Patients with psoriasis should receive a COVID vaccine as soon as one is available.