Perinatal Hemolytic Disorders and Identification Using End Tidal Breath Carbon Monoxide
4
Issued Date
2023-11-01
Resource Type
ISSN
15733963
eISSN
18756336
Scopus ID
2-s2.0-85146257821
Pubmed ID
36545740
Journal Title
Current Pediatric Reviews
Volume
19
Issue
4
Start Page
376
End Page
387
Rights Holder(s)
SCOPUS
Bibliographic Citation
Current Pediatric Reviews Vol.19 No.4 (2023) , 376-387
Suggested Citation
Christensen R.D., Bahr T.M., Pakdeeto S., Supapannachart S., Zhang H. Perinatal Hemolytic Disorders and Identification Using End Tidal Breath Carbon Monoxide. Current Pediatric Reviews Vol.19 No.4 (2023) , 376-387. 387. doi:10.2174/1573396319666221220095522 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/82036
Title
Perinatal Hemolytic Disorders and Identification Using End Tidal Breath Carbon Monoxide
Other Contributor(s)
Abstract
Hemolytic disorders can cause severe morbidity or can be life-threatening. Before the re-cent development of practical and inexpensive testing for hemolysis by quantifying carbon monoxide in end-tidal breath, some hemolytic disorders in perinatal patients were not detected until se-verely problematic hyperbilirubinemia and/or anemia occurred. Here we review studies aimed at es-tablishing the normal reference intervals for end tidal breath carbon monoxide (ETCO) in various perinatal populations. We also review reports, and new theories, about using this methodology to diagnose and quantify hemolytic disorders in term and premature neonates, anemic pregnant wom-en, and fetuses in utero. The purposes of making these measurements are to; (1) identify patients who have hemolytic disorders, (2) characterize the severity of the hemolysis in each hemolytic pa-tient, and (3) predict and prevent co-morbidities, thereby improving outcomes.